Matches in SemOpenAlex for { <https://semopenalex.org/work/W1174212708> ?p ?o ?g. }
- W1174212708 endingPage "85" @default.
- W1174212708 startingPage "978" @default.
- W1174212708 abstract "The effect of graded doses (0.125, 0.500, 1.00 and 2.00 mug per kg per hr) of intravenous synthetic human gastrin I (SHG) on jejunal transport of water, electrolytes, and glucose from a glucose-saline solution (solution II) was studied in 12 healthy volunteers, using an intestinal perfusion technique with a proximal occluding balloon. SHG when infused at rates of 0.500 mug per kg per hr or greater significantly reduced water and electrolyte absorption; this effect was linearly related to the dose and reached 40 to 60% of basal absorption (and only 10% for glucose) with the highest dose; insorption of sodium and water were significantly decreased by SHG. In a further group of 9 subjects no effect of SHG (2 mug per kg per hr) was found on jejunal absorption from a mannitol-saline solution (solution I) and on ileal absorption from solutions I and II; in 5 additional subjects, SHG did not decrease jejunal transit time of intraluminal fluid. There was no increase in serum thyrocalcitonin during SHG infusion. It is proposed that SHG selectively depresses the glucose-stimulated sodium transport as suggested by the reduction of the rate of net sodium absorption per micromole of glucose absorbed during SHG infusion. Physiological and pathological implications of these findings are discussed, especially in the light of the circulating levels of immunoreactive gastrin achieved during SHG infusion." @default.
- W1174212708 created "2016-06-24" @default.
- W1174212708 creator A5015328535 @default.
- W1174212708 creator A5036870609 @default.
- W1174212708 creator A5084884091 @default.
- W1174212708 date "1976-12-01" @default.
- W1174212708 modified "2023-10-17" @default.
- W1174212708 title "Effects of synthetic human gastrin I on movements on water, electrolytes, and glucose across the human small intestine." @default.
- W1174212708 cites W1120496478 @default.
- W1174212708 cites W1567610244 @default.
- W1174212708 cites W1897931885 @default.
- W1174212708 cites W2014214666 @default.
- W1174212708 cites W2022520225 @default.
- W1174212708 cites W2022992512 @default.
- W1174212708 cites W2052558405 @default.
- W1174212708 cites W2054167101 @default.
- W1174212708 cites W2057797584 @default.
- W1174212708 cites W2072093345 @default.
- W1174212708 cites W2091461192 @default.
- W1174212708 cites W2094354821 @default.
- W1174212708 cites W2113358892 @default.
- W1174212708 cites W2115605134 @default.
- W1174212708 cites W2119645046 @default.
- W1174212708 cites W2133630112 @default.
- W1174212708 cites W2143822991 @default.
- W1174212708 cites W2149292158 @default.
- W1174212708 cites W2168545891 @default.
- W1174212708 cites W2170065097 @default.
- W1174212708 cites W2179998239 @default.
- W1174212708 cites W2409055268 @default.
- W1174212708 cites W2415147931 @default.
- W1174212708 cites W2416252417 @default.
- W1174212708 cites W2416319386 @default.
- W1174212708 cites W2416343941 @default.
- W1174212708 cites W2420076999 @default.
- W1174212708 cites W2421280133 @default.
- W1174212708 cites W2422630636 @default.
- W1174212708 cites W2472685179 @default.
- W1174212708 cites W2941019189 @default.
- W1174212708 cites W2941696551 @default.
- W1174212708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/992281" @default.
- W1174212708 hasPublicationYear "1976" @default.
- W1174212708 type Work @default.
- W1174212708 sameAs 1174212708 @default.
- W1174212708 citedByCount "6" @default.
- W1174212708 crossrefType "journal-article" @default.
- W1174212708 hasAuthorship W1174212708A5015328535 @default.
- W1174212708 hasAuthorship W1174212708A5036870609 @default.
- W1174212708 hasAuthorship W1174212708A5084884091 @default.
- W1174212708 hasConcept C125287762 @default.
- W1174212708 hasConcept C126322002 @default.
- W1174212708 hasConcept C134018914 @default.
- W1174212708 hasConcept C146957229 @default.
- W1174212708 hasConcept C147789679 @default.
- W1174212708 hasConcept C159985019 @default.
- W1174212708 hasConcept C168314062 @default.
- W1174212708 hasConcept C17525397 @default.
- W1174212708 hasConcept C178790620 @default.
- W1174212708 hasConcept C185592680 @default.
- W1174212708 hasConcept C192562407 @default.
- W1174212708 hasConcept C2776366702 @default.
- W1174212708 hasConcept C2776986829 @default.
- W1174212708 hasConcept C2777397205 @default.
- W1174212708 hasConcept C2778445172 @default.
- W1174212708 hasConcept C49039625 @default.
- W1174212708 hasConcept C537181965 @default.
- W1174212708 hasConcept C55493867 @default.
- W1174212708 hasConcept C59822182 @default.
- W1174212708 hasConcept C68801617 @default.
- W1174212708 hasConcept C71924100 @default.
- W1174212708 hasConcept C86803240 @default.
- W1174212708 hasConceptScore W1174212708C125287762 @default.
- W1174212708 hasConceptScore W1174212708C126322002 @default.
- W1174212708 hasConceptScore W1174212708C134018914 @default.
- W1174212708 hasConceptScore W1174212708C146957229 @default.
- W1174212708 hasConceptScore W1174212708C147789679 @default.
- W1174212708 hasConceptScore W1174212708C159985019 @default.
- W1174212708 hasConceptScore W1174212708C168314062 @default.
- W1174212708 hasConceptScore W1174212708C17525397 @default.
- W1174212708 hasConceptScore W1174212708C178790620 @default.
- W1174212708 hasConceptScore W1174212708C185592680 @default.
- W1174212708 hasConceptScore W1174212708C192562407 @default.
- W1174212708 hasConceptScore W1174212708C2776366702 @default.
- W1174212708 hasConceptScore W1174212708C2776986829 @default.
- W1174212708 hasConceptScore W1174212708C2777397205 @default.
- W1174212708 hasConceptScore W1174212708C2778445172 @default.
- W1174212708 hasConceptScore W1174212708C49039625 @default.
- W1174212708 hasConceptScore W1174212708C537181965 @default.
- W1174212708 hasConceptScore W1174212708C55493867 @default.
- W1174212708 hasConceptScore W1174212708C59822182 @default.
- W1174212708 hasConceptScore W1174212708C68801617 @default.
- W1174212708 hasConceptScore W1174212708C71924100 @default.
- W1174212708 hasConceptScore W1174212708C86803240 @default.
- W1174212708 hasIssue "6" @default.
- W1174212708 hasLocation W11742127081 @default.
- W1174212708 hasOpenAccess W1174212708 @default.
- W1174212708 hasPrimaryLocation W11742127081 @default.
- W1174212708 hasRelatedWork W1174212708 @default.