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- W1174647490 abstract "Pattern-recognition receptors (PRRs) can detect various pathogen-associated molecular patterns such as carbohydrates, nucleic acids or bacterial peptides and play a major role in both innate and adaptive immunity. In physiological conditions, the engagement of PRRs triggers the production of proinflammatory cytokines and promotes pathogen destruction. Inappropriate stimulation or defective regulation of PRR has been recently evidenced in several inherited inflammatory disorders. This new field of childhood-onset inflammatory diseases encompass the so-called type-I interferon-related diseases and autoinflammatory diseases." @default.
- W1174647490 created "2016-06-24" @default.
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- W1174647490 date "2015-12-01" @default.
- W1174647490 modified "2023-10-06" @default.
- W1174647490 title "Inherited anomalies of innate immune receptors in pediatric-onset inflammatory diseases" @default.
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- W1174647490 doi "https://doi.org/10.1016/j.autrev.2015.08.002" @default.
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