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- W117540123 abstract "Abstract : Plants have cholinesterases (pChEs), anti-ChEs, and activators of ChEs. We have isolated pChE from mung bean sprout. We investigated 300 plants and found that 75% of them contained anti- ChE that inhibited ChEs. Thirty-five percent contained activators of ChEs. An activator of ChE from wheat leaf, Tritiacche-T123 , activates fetal bovine serum AChE, equine BChE, and pChE. This non-oxime natural plant product may offer a new approach to the reactivation of OP-inhibited ChEs. pChE showed substrate differences from human acetylcholinesterase (AChE) or butyrylcholinesterase, hydrolyzing propionylthiocholine > acetylthiocholine > butyrylthiocholine. pChEs might also be useful as bioscavengers of OP nerve agents." @default.
- W117540123 created "2016-06-24" @default.
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- W117540123 date "2005-10-01" @default.
- W117540123 modified "2023-09-27" @default.
- W117540123 title "Detoxification of Chemical Warfare Agents by the Plant Cholinergic System" @default.
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