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• W117597304 abstract "During early developmental stages the brain is more vulnerable to physiological insult than the more mature brain. However, an early diagnosis of deficits might enhance the chances for successful interventions due to the high cortical plasticity of the immature brain. This thesis contains two studies on early cognitive development, conducted with a device called fetal magnetoencephalography (fMEG). It allows non-invasive recordings of cortical responses in utero. Objective: Two study paradigms that assess cognitive functioning, such as integrative processes and the development of speech perception, were applied to neonates and fetuses. Methods: In study 1, brain responses to visual stimuli (VER) in a habituation paradigm were recorded in 25 fetuses (aged between 29 and 37 weeks gestational age (GA)) and 12 newborns (aged between 6 and 22 days). In study 2, auditory evoked responses (AER) to tone pairs were presented to 22 fetuses (aged between 29 and 38 weeks GA) and 15 neonates (aged between 2 and 38 days). This paradigm was applied in two difficulties – with short and long gaps between the tones. In both studies, the newborns already participated in the corresponding antecedent fetal recordings. Results: In study 1, nine of the 12 newborns showed a response decrement for consecutive visual stimuli, indicating habituation. The remaining three recordings were discontinued Early Development 7 early. The prenatal VER rate was only 29%. But these fetuses exhibited a response decrement as well. In study 2, the newborns showed a trend to 2 responses with increasing age in the long gap tone pair. The prenatal study revealed single responses in most cases and no trend was observed. However, the fetal response rate between 76% and 86% was higher than in previous studies. Conclusions: Both paradigms have been successfully applied on neonates and fetuses, and cortical responses were recorded with fMEG technology. Despite the challenges in fetal data analysis, these investigations might help to improve future study paradigms and technological advances. Significance: These studies might contribute to a more accurate detection of early developmental delays and the development of subsequent impairments. Early Development 8 ACKNOWLEDGEMENTS The present investigations were conducted at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, Arkansas, in close collaboration with the MEG Center in Tubingen, Germany. Both were funded by the National Institutes of Health (NIH). I express deepest thanks to my supervisor Dr. Hubert Preissl, who always provided great support and encouragement beyond the standard requirements. I am very grateful to the people from the SARA Lab, who continuously offered their personal and professional advice with patience and warmth: Dr. Hari Eswaran, Maureen Ware, Pamela Murphy, Dr. Joshua Campbell, Dr. Isabelle Kiefer, Mike Oglesby, Eric Siegel and Dr. Curtis Lowery. I express my sincere thanks to Dr. Karin Landerl and Professor Dr. Niels Birbaumer for their help and support. I am indebted to Dr. Rossitza Draganova, who was very helpful with professional and personal advice. Early Development 9 Last but not least, I thank my family and friends who are always there for me, inspire me, support me, or just listen: my husband, Jeff Sheridan, my parents, Werner and Angelika Schaller, my friends, Stephanie Bald, Bianca Puppatti, Kirsten Lindner, Yvonne Zahumensky and Cornelia Weber. December, 2007 Carolin J. Sheridan Early Development 10 -" @default.
• W117597304 created "2016-06-24" @default.
• W117597304 creator A5000711781 @default.
• W117597304 date "2008-01-01" @default.
• W117597304 modified "2023-09-26" @default.
• W117597304 title "Early development of cortical brain responses in newborns and fetuses – cognitive studies with fetal magnetoencephalography" @default.
• W117597304 cites W1525020787 @default.
• W117597304 cites W1557058046 @default.
• W117597304 cites W1606727621 @default.
• W117597304 cites W1737567839 @default.
• W117597304 cites W1964240517 @default.
• W117597304 cites W1966298199 @default.
• W117597304 cites W1966331718 @default.
• W117597304 cites W1966443930 @default.
• W117597304 cites W1967561443 @default.
• W117597304 cites W1968656090 @default.
• W117597304 cites W1968826917 @default.
• W117597304 cites W1970725316 @default.
• W117597304 cites W1971880456 @default.
• W117597304 cites W1972266243 @default.
• W117597304 cites W1973052225 @default.
• W117597304 cites W1976997087 @default.
• W117597304 cites W1978878791 @default.
• W117597304 cites W1979521920 @default.
• W117597304 cites W1980458777 @default.
• W117597304 cites W1980551232 @default.
• W117597304 cites W1982321167 @default.
• W117597304 cites W1983602525 @default.
• W117597304 cites W1984509243 @default.
• W117597304 cites W1985125696 @default.
• W117597304 cites W1985395852 @default.
• W117597304 cites W1988747931 @default.
• W117597304 cites W1989769398 @default.
• W117597304 cites W1990292225 @default.
• W117597304 cites W1990523086 @default.
• W117597304 cites W1990783647 @default.
• W117597304 cites W1992898741 @default.
• W117597304 cites W1993576637 @default.
• W117597304 cites W1994003407 @default.
• W117597304 cites W1994408731 @default.
• W117597304 cites W1997849248 @default.
• W117597304 cites W1997983856 @default.
• W117597304 cites W1999875375 @default.
• W117597304 cites W2000130602 @default.
• W117597304 cites W2000237968 @default.
• W117597304 cites W2001279676 @default.
• W117597304 cites W2002826609 @default.
• W117597304 cites W2003302638 @default.
• W117597304 cites W2003355909 @default.
• W117597304 cites W2003843523 @default.
• W117597304 cites W2005044375 @default.
• W117597304 cites W2005447114 @default.
• W117597304 cites W2005571224 @default.
• W117597304 cites W2006806818 @default.
• W117597304 cites W2007834479 @default.
• W117597304 cites W2007866766 @default.
• W117597304 cites W2009407666 @default.
• W117597304 cites W2010104112 @default.
• W117597304 cites W2013097787 @default.
• W117597304 cites W2013378169 @default.
• W117597304 cites W2015341540 @default.
• W117597304 cites W2015440989 @default.
• W117597304 cites W2015927490 @default.
• W117597304 cites W2016232758 @default.
• W117597304 cites W2021107445 @default.
• W117597304 cites W2024089375 @default.
• W117597304 cites W2026060111 @default.
• W117597304 cites W2028287085 @default.
• W117597304 cites W2028827364 @default.
• W117597304 cites W2034177015 @default.
• W117597304 cites W2034759911 @default.
• W117597304 cites W2035126305 @default.
• W117597304 cites W2042092388 @default.
• W117597304 cites W2042681240 @default.
• W117597304 cites W2044073787 @default.
• W117597304 cites W2050045067 @default.
• W117597304 cites W2050535708 @default.
• W117597304 cites W2051361830 @default.
• W117597304 cites W2054692302 @default.
• W117597304 cites W2055171682 @default.
• W117597304 cites W2059643265 @default.
• W117597304 cites W2059884445 @default.
• W117597304 cites W2060087675 @default.
• W117597304 cites W2065415205 @default.
• W117597304 cites W2068027490 @default.
• W117597304 cites W2068231558 @default.
• W117597304 cites W2069364303 @default.
• W117597304 cites W2069474802 @default.
• W117597304 cites W2074717568 @default.
• W117597304 cites W2075387429 @default.
• W117597304 cites W2076495877 @default.
• W117597304 cites W2077728451 @default.
• W117597304 cites W2081640908 @default.
• W117597304 cites W2085142694 @default.
• W117597304 cites W2091400877 @default.
• W117597304 cites W2091964153 @default.
• W117597304 cites W2095055989 @default.
• W117597304 cites W2095796823 @default.
• W117597304 cites W2096587741 @default.
• W117597304 cites W2105732570 @default.

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