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• W1181639237 abstract "Hepatitis C virus (HCV) genotypes 2 and 3 have previously been classified as easy-to-treat genotypes, because sustained virologic responses (SVRs) up to 80% have been achieved with 24-week peginterferon and ribavirin. More detailed studies have shown differences between HCV genotypes 2 and 3, indicating that genotype 3 has become the most difficult-to-treat genotype. With new drugs, new challenges are emerging regarding relapse rates, the role of ribavirin, and optimal duration of therapy. Sofosbuvir remains the backbone of genotype 3 therapy, whereas this drug is not an option in patients with creatinine clearance lower than 30 mL/min." @default.
• W1181639237 created "2016-06-24" @default.
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• W1181639237 date "2015-12-01" @default.
• W1181639237 modified "2023-09-27" @default.
• W1181639237 title "Hepatitis C Virus" @default.
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• W1181639237 doi "https://doi.org/10.1016/j.gtc.2015.07.009" @default.
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