Matches in SemOpenAlex for { <https://semopenalex.org/work/W1182578890> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1182578890 endingPage "3509" @default.
- W1182578890 startingPage "3509" @default.
- W1182578890 abstract "Purpose: The broad-slow-rising entrance dose region proximal to the Bragg peak made by a mono-energetic proton beam could potentially be used for total body irradiation (TBI). Due to the quasi-uniform dose deposition, customized thickness compensation may not be required to deliver a uniform dose to patients with varied thickness. We investigated the possibility, efficacy, and hardware requirement to use such proton beam for TBI. Methods: A wedge shaped water phantom with thickness varying from 2 cm to 40 cm was designed to mimic a patient. Geant4 based Monte Carlo code was used to simulate broad mono-energetic proton beams with energy ranging from 250 MeV to 300 MeV radiating the phantom. A 6 MV photon with 1 cm water equivalent build-up used for conventional TBI was also calculated. A paired-opposing beam arrangement with no thickness compensation was used to generate TBI plans for all beam energies. Dose from all particles were scored on a grid size of 2 mm3. Dose uniformity across the phantom was calculated to evaluate the plan. The field size limit and the dose uniformity of Mevion S250 proton system was examined by using radiochromic films placed at extended treatment distance with the open large applicator and 90° gantry angle. Results: To achieve a maximum ± 7.5% dose variation, the largest patient thickness variation allowed for 250 MeV, 275 MeV, and 300 MeV proton beams were 27.0 cm, 34.9 cm and 36.7 cm. The value for 6 MV photon beam was only 8.0 cm to achieve the same dose variation. With open gantry, Mevion S250 system allows 5 m source-to-surface distance producing an expected 70 cm2 field size. Conclusion: Energetic proton beam can potentially be used to deliver TBI. Treatment planning and delivery would be much simple since no thickness compensation is required to achieve a uniform dose distribution." @default.
- W1182578890 created "2016-06-24" @default.
- W1182578890 creator A5004465495 @default.
- W1182578890 creator A5036836887 @default.
- W1182578890 creator A5059269600 @default.
- W1182578890 creator A5063474152 @default.
- W1182578890 date "2015-06-01" @default.
- W1182578890 modified "2023-09-27" @default.
- W1182578890 title "SU-E-T-748: Theoretical Investigation On Using High Energy Proton Beam for Total-Body-Irradiation" @default.
- W1182578890 doi "https://doi.org/10.1118/1.4925112" @default.
- W1182578890 hasPublicationYear "2015" @default.
- W1182578890 type Work @default.
- W1182578890 sameAs 1182578890 @default.
- W1182578890 citedByCount "0" @default.
- W1182578890 crossrefType "journal-article" @default.
- W1182578890 hasAuthorship W1182578890A5004465495 @default.
- W1182578890 hasAuthorship W1182578890A5036836887 @default.
- W1182578890 hasAuthorship W1182578890A5059269600 @default.
- W1182578890 hasAuthorship W1182578890A5063474152 @default.
- W1182578890 hasConcept C104293457 @default.
- W1182578890 hasConcept C105795698 @default.
- W1182578890 hasConcept C111337013 @default.
- W1182578890 hasConcept C120665830 @default.
- W1182578890 hasConcept C121332964 @default.
- W1182578890 hasConcept C168834538 @default.
- W1182578890 hasConcept C185544564 @default.
- W1182578890 hasConcept C192562407 @default.
- W1182578890 hasConcept C19499675 @default.
- W1182578890 hasConcept C2779244869 @default.
- W1182578890 hasConcept C2780944729 @default.
- W1182578890 hasConcept C2781298738 @default.
- W1182578890 hasConcept C2989005 @default.
- W1182578890 hasConcept C33923547 @default.
- W1182578890 hasConcept C47422493 @default.
- W1182578890 hasConcept C54516573 @default.
- W1182578890 hasConcept C71924100 @default.
- W1182578890 hasConcept C75088862 @default.
- W1182578890 hasConceptScore W1182578890C104293457 @default.
- W1182578890 hasConceptScore W1182578890C105795698 @default.
- W1182578890 hasConceptScore W1182578890C111337013 @default.
- W1182578890 hasConceptScore W1182578890C120665830 @default.
- W1182578890 hasConceptScore W1182578890C121332964 @default.
- W1182578890 hasConceptScore W1182578890C168834538 @default.
- W1182578890 hasConceptScore W1182578890C185544564 @default.
- W1182578890 hasConceptScore W1182578890C192562407 @default.
- W1182578890 hasConceptScore W1182578890C19499675 @default.
- W1182578890 hasConceptScore W1182578890C2779244869 @default.
- W1182578890 hasConceptScore W1182578890C2780944729 @default.
- W1182578890 hasConceptScore W1182578890C2781298738 @default.
- W1182578890 hasConceptScore W1182578890C2989005 @default.
- W1182578890 hasConceptScore W1182578890C33923547 @default.
- W1182578890 hasConceptScore W1182578890C47422493 @default.
- W1182578890 hasConceptScore W1182578890C54516573 @default.
- W1182578890 hasConceptScore W1182578890C71924100 @default.
- W1182578890 hasConceptScore W1182578890C75088862 @default.
- W1182578890 hasIssue "6Part24" @default.
- W1182578890 hasLocation W11825788901 @default.
- W1182578890 hasOpenAccess W1182578890 @default.
- W1182578890 hasPrimaryLocation W11825788901 @default.
- W1182578890 hasRelatedWork W1612657723 @default.
- W1182578890 hasRelatedWork W1981134902 @default.
- W1182578890 hasRelatedWork W2018352805 @default.
- W1182578890 hasRelatedWork W2040264181 @default.
- W1182578890 hasRelatedWork W2052545816 @default.
- W1182578890 hasRelatedWork W2390434854 @default.
- W1182578890 hasRelatedWork W2599813757 @default.
- W1182578890 hasRelatedWork W3029117906 @default.
- W1182578890 hasRelatedWork W3092451929 @default.
- W1182578890 hasRelatedWork W2116284379 @default.
- W1182578890 hasVolume "42" @default.
- W1182578890 isParatext "false" @default.
- W1182578890 isRetracted "false" @default.
- W1182578890 magId "1182578890" @default.
- W1182578890 workType "article" @default.