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- W118317335 abstract "ABSTRACT In the pineal of 10, 21 and 42 day old male Wistar rats hydroxyindole-O-methyltransferase (HIOMT) activities involved in the synthesis of several 5-methoxyindoles were investigated during the night in April, June, October and January. It was observed that during January and April melatonin/5-methoxytryptophol and 5-methoxytryptophan synthesis was highest. The synthesis of 5-methoxytryptamine and 5-me”thoxyindole-3-acetic acid does not coincide with melatonin/5-methoxytryptophol and 5-methoxytryptophan synthesis. Furthermore it was demonstrated that the maxima of HIOMT activities change in time during the seasons. The seasonal variations in HIOMT activity and a shift of the activity maxima demonstrate that indole metabolism is more complicated than is generally accepted." @default.
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- W118317335 date "1981-01-01" @default.
- W118317335 modified "2023-09-27" @default.
- W118317335 title "Seasonal Variations in HIOMT Activity During the Night in the Pineal Gland of Wistar Rats of Several Ages" @default.
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- W118317335 doi "https://doi.org/10.1016/b978-0-08-026400-4.50032-3" @default.
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