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- W118566120 abstract "The present report demonstrates that substance P and the hypothalamic-releasing hormone, TRH, which has been shown by immunohistochemical techniques to be localized within nerve terminals ending in the vicinity of spinal motoneurons, have an excitatory action on motoneurons with a potency approaching that of glutamate. The actions of substance P and TRH also resemble glutamate in that they often increase the conductance of the membrane. However, the responses differ from those of glutamate in two respects. Their actions are of long duration and the maximum depolarization rarely surpasses threshold. These results suggest that substance P and TRH provide a background facilitation of motoneurons." @default.
- W118566120 created "2016-06-24" @default.
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- W118566120 date "1978-01-01" @default.
- W118566120 modified "2023-10-17" @default.
- W118566120 title "THE EXCITATORY ACTION OF SUBSTANCE P AND TRH ON SPINAL MOTONEURONS" @default.
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- W118566120 doi "https://doi.org/10.1016/b978-1-4832-8322-7.50081-9" @default.
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