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- W1189205771 abstract "The cell membrane is considered as a passive structure allowing solutes to penetrate according to the properties of their molecules, such as size, membrane solubility, and electric charge. Membrane is a part of the cell machinery, which contains special enzymes, participating both in the control of cell metabolism and in the transport of substances. The essential feature of an enzymatically controlled transport is a combined action of two surface enzymes separated by the cell membrane, whereby the substrate is temporarily changed to a membrane-soluble transport form capable of penetrating the membrane. The identification of a transport as enzymatically controlled meets with greater difficulties if it is not thermodynamically active. Indirect criteria then have to be used. They include (1) non-conformity with the laws of diffusion, particularly a constant penetration rate independent of the concentration difference, (2) competition of simultaneously penetrating substrates, (3) high structural specificity, particularly stereospecificity, and (4) action of enzyme effectors (inhibitors or activators) on the rate of transport." @default.
- W1189205771 created "2016-06-24" @default.
- W1189205771 creator A5005662900 @default.
- W1189205771 creator A5044225891 @default.
- W1189205771 date "1952-01-01" @default.
- W1189205771 modified "2023-09-23" @default.
- W1189205771 title "Enzymatic Processes in Cell Membrane Penetration" @default.
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- W1189205771 doi "https://doi.org/10.1016/s0074-7696(08)60005-4" @default.
- W1189205771 hasPublicationYear "1952" @default.
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