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- W1191232643 abstract "This chapter discusses new chemical entities (NCEs), for human therapeutic use, introduced for the first time during 1992 into the world marketplace. Number of total entities had been found to be 36. Some of the marketable products under discussion are aceclofenac, beraprost sodium, cefetamet pivoxil hydrochloride, desflurane, finasteride, lodoxarn.de trometham’ne, mivacurium chloride, pentostatin, rufloxacin hydrochloride, tilisolol hydrochloride, and zalcitabine. Each compound is documented as product name, trade name, first introduction, introduced by, originator, country of origin, and chemical abstracts service (CAS) registry number. Some of the classifications the chapter points for every compounds include anti-viral, anti-inflammatory, anti-hypertensive, mucolytic, β-lactamase inhibitor, topical anti-fungal, anti-bacterial, urologic, anti-neoplastic, muscle relaxant, and anti-allergic ophthalmic. Approximately 60% of the new NCEs launched in 1992 originated in two countries; 13 in Japan and 8 in the United States while the United Kingdom had 5 with Spain, Germany, and Italy, 3 each. Novel NCEs of special interest representing new classes of compounds include finasteride, the first agent for the treatment of benign prostatic hyperplasia; flosequinan, for congestive heart failure; and dexrazoxane, an adjuvant for reducing the cardiac side effects associated with the anti-cancer anthracyclines." @default.
- W1191232643 created "2016-06-24" @default.
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- W1191232643 date "1993-01-01" @default.
- W1191232643 modified "2023-09-23" @default.
- W1191232643 title "Chapter 34. To Market, To Market – 1992" @default.
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- W1191232643 doi "https://doi.org/10.1016/s0065-7743(08)60904-5" @default.
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