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- W1194291995 abstract "Circadian rhythms are recurring patterns in a host of physiological and other parameters that recur with periods of near 24 h. These rhythms reflect the temporal organization of an organism's homeostatic control systems and as such are key processes in ensuring optimal physiological performance. Dysfunction of circadian processes is linked with adverse health conditions. In this review we highlight the evidence that normal, healthy aging is associated with changes in the circadian system; we examine the molecular mechanisms through which such changes may arise, discuss whether more robust circadian function is a predictor of longevity and highlight the role of circadian rhythms in age-related diseases. Overall, the literature shows that aging is associated with marked changes in circadian processes, both at the behavioral and molecular levels, and the molecular mechanisms through which such changes arise remain to be elucidated, but may involve inflammatory process, redox homeostasis and epigenetic modifications. Understanding the nature of age-related circadian dysfunction will allow for the design of chronotherapeutic intervention strategies to attenuate circadian dysfunction and thus improve health and quality of life." @default.
- W1194291995 created "2016-06-24" @default.
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- W1194291995 date "2015-07-15" @default.
- W1194291995 modified "2023-10-18" @default.
- W1194291995 title "How does healthy aging impact on the circadian clock?" @default.
- W1194291995 cites W1514968045 @default.
- W1194291995 cites W1532216753 @default.
- W1194291995 cites W1585908178 @default.
- W1194291995 cites W1599101054 @default.
- W1194291995 cites W1754426294 @default.
- W1194291995 cites W177946920 @default.
- W1194291995 cites W1841116434 @default.
- W1194291995 cites W1964949721 @default.
- W1194291995 cites W1969904423 @default.
- W1194291995 cites W1972197632 @default.
- W1194291995 cites W1973056324 @default.
- W1194291995 cites W1973121474 @default.
- W1194291995 cites W1975982492 @default.
- W1194291995 cites W1977518394 @default.
- W1194291995 cites W1981579010 @default.
- W1194291995 cites W1982181206 @default.
- W1194291995 cites W1983076902 @default.
- W1194291995 cites W1983771401 @default.
- W1194291995 cites W1984497856 @default.
- W1194291995 cites W1985604755 @default.
- W1194291995 cites W1987699071 @default.
- W1194291995 cites W1988374824 @default.
- W1194291995 cites W1988831545 @default.
- W1194291995 cites W1989496648 @default.
- W1194291995 cites W1989699759 @default.
- W1194291995 cites W1992123148 @default.
- W1194291995 cites W1993901564 @default.
- W1194291995 cites W1995377942 @default.
- W1194291995 cites W1996955271 @default.
- W1194291995 cites W1999021226 @default.
- W1194291995 cites W2003062381 @default.
- W1194291995 cites W2004477770 @default.
- W1194291995 cites W2007072149 @default.
- W1194291995 cites W2011072921 @default.
- W1194291995 cites W2014069918 @default.
- W1194291995 cites W2016069734 @default.
- W1194291995 cites W2016711283 @default.
- W1194291995 cites W2017564803 @default.
- W1194291995 cites W2019690505 @default.
- W1194291995 cites W2028499883 @default.
- W1194291995 cites W2033565755 @default.
- W1194291995 cites W2034831738 @default.
- W1194291995 cites W2038533484 @default.
- W1194291995 cites W2038561307 @default.
- W1194291995 cites W2040618107 @default.
- W1194291995 cites W2042482597 @default.
- W1194291995 cites W2043888433 @default.
- W1194291995 cites W2044315129 @default.
- W1194291995 cites W2045464191 @default.
- W1194291995 cites W2046980737 @default.
- W1194291995 cites W2047925853 @default.
- W1194291995 cites W2049638450 @default.
- W1194291995 cites W2061602407 @default.
- W1194291995 cites W2069473378 @default.
- W1194291995 cites W2077627314 @default.
- W1194291995 cites W2078978479 @default.
- W1194291995 cites W2079302130 @default.
- W1194291995 cites W2079320127 @default.
- W1194291995 cites W2082825725 @default.
- W1194291995 cites W2084306210 @default.
- W1194291995 cites W2085483223 @default.
- W1194291995 cites W2086587912 @default.
- W1194291995 cites W2087067458 @default.
- W1194291995 cites W2088901701 @default.
- W1194291995 cites W2091531174 @default.
- W1194291995 cites W2094874423 @default.
- W1194291995 cites W2098009444 @default.
- W1194291995 cites W2101600063 @default.
- W1194291995 cites W2104605616 @default.
- W1194291995 cites W2106881313 @default.
- W1194291995 cites W2107668207 @default.
- W1194291995 cites W2108988707 @default.
- W1194291995 cites W2109504679 @default.
- W1194291995 cites W2109664949 @default.
- W1194291995 cites W2109945695 @default.
- W1194291995 cites W2111173867 @default.
- W1194291995 cites W2114238611 @default.
- W1194291995 cites W2121847288 @default.
- W1194291995 cites W2123106689 @default.
- W1194291995 cites W2124737554 @default.
- W1194291995 cites W2126291641 @default.
- W1194291995 cites W2131882669 @default.
- W1194291995 cites W2136102778 @default.
- W1194291995 cites W2136921993 @default.
- W1194291995 cites W2138292762 @default.
- W1194291995 cites W2143210222 @default.
- W1194291995 cites W2146586614 @default.