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- W11971787 endingPage "5101" @default.
- W11971787 startingPage "5101" @default.
- W11971787 abstract "Infection with H pylori is the most important known etiological factor associated with gastric cancer. While colonization of the gastric mucosa with H pylori results in active and chronic gastritis in virtually all individuals infected, the likelihood of developing gastric cancer depends on environmental, bacterial virulence and host specific factors. The majority of all gastric cancer cases are attributable to H pylori infection and therefore theoretically preventable. There is evidence from animal models that eradication of H pylori at an early time point can prevent gastric cancer development. However, randomized clinical trials exploring the prophylactic effect of H pylori eradication on the incidence of gastric cancer in humans remain sparse and have yielded conflicting results. Better markers for the identification of patients at risk for H pylori induced gastric malignancy are needed to allow the development of a more efficient public eradication strategy. Meanwhile, screening and treatment of H pylori in first-degree relatives of gastric cancer patients as well as certain high-risk populations might be beneficial." @default.
- W11971787 created "2016-06-24" @default.
- W11971787 creator A5054331215 @default.
- W11971787 creator A5068561527 @default.
- W11971787 creator A5076835443 @default.
- W11971787 date "2006-01-01" @default.
- W11971787 modified "2023-09-27" @default.
- W11971787 title "Eradication ofH pylorifor the prevention of gastric cancer" @default.
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