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- W12009417 abstract "This chapter presents the cellular basis of the immune response. The main function of the immune system is to make specific responses against molecules identifiable as foreign. The possession of cells with specific receptors and an ability to discriminate between self and nonself is essential for this function. There are two arms of the immune response, the cellular and the humoral. Their control is tightly linked but they show certain distinctive features that reflect the effector cell types mediating them. Humoral immunity means antibody responses, the secreted immunoglobulins that are carried through the body via the blood circulation and tissue fluids from their site of manufacture by B lymphocytes. Cellular immunity means a group of responses such as graft rejection, delayed type hypersensitivity and Tc responses, carried out or initiated by the various subpopulations of T lymphocytes. Humoral and cellular immune responses are interconnected in the senses that almost all B cell responses require T cell help, and that the presence of each type of response to determinants on the same foreign antigen modifies the other. However, B lymphocytes are different from T lymphocytes with respect to their specific receptors and their triggering requirements." @default.
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- W12009417 date "1984-01-01" @default.
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- W12009417 title "THE CELLULAR BASIS OF THE IMMUNE RESPONSE" @default.
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- W12009417 doi "https://doi.org/10.1016/b978-0-408-10865-2.50006-2" @default.
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