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- W1205325697 abstract "Dynamic causal modelling (DCM) has extended the understanding of brain network dynamics in a variety of functional systems. In the motor system, DCM studies based on functional magnetic resonance imaging (fMRI) or on magneto-/electroencephalography (M/EEG) have demonstrated movement-related causal information flow from secondary to primary motor areas and have provided evidence for nonlinear cross-frequency interactions among motor areas. The present study sought to investigate to what extent fMRI- and EEG-based DCM might provide complementary and synergistic insights into neuronal network dynamics. Both modalities share principal similarities in the formulation of the DCM. Thus, we hypothesized that DCM based on induced EEG responses (DCM-IR) and on fMRI would reveal congruent task-dependent network dynamics. Brain electrical (63-channel surface EEG) and Blood Oxygenation Level Dependent (BOLD) signals were recorded in separate sessions from 14 healthy participants performing simple isometric right and left hand grips. DCM-IR and DCM-fMRI were used to estimate coupling parameters modulated by right and left hand grips within a core motor network of six regions comprising bilateral primary motor cortex (M1), ventral premotor cortex (PMv) and supplementary motor area (SMA). We found that DCM-fMRI and DCM-IR similarly revealed significant grip-related increases in facilitatory coupling between SMA and M1 contralateral to the active hand. A grip-dependent interhemispheric reciprocal inhibition between M1 bilaterally was only revealed by DCM-fMRI but not by DCM-IR. Frequency-resolved coupling analysis showed that the information flow from contralateral SMA to M1 was predominantly a linear alpha-to-alpha (9-13Hz) interaction. We also detected some cross-frequency coupling from SMA to contralateral M1, i.e., between lower beta (14-21Hz) at the SMA and higher beta (22-30Hz) at M1 during right hand grip and between alpha (9-13Hz) at SMA and lower beta (14-21Hz) at M1 during left hand grip. In conclusion, the strategy of informing EEG source-space configurations with fMRI-derived coordinates, cross-validating basic connectivity maps and analysing frequency coding allows for deeper insight into the motor network architecture of the human brain. The present results provide evidence for the robustness of non-invasively measured causal information flow from secondary motor areas such as SMA towards M1 and further contribute to the validation of the methodological approach of multimodal DCM to explore human network dynamics." @default.
- W1205325697 created "2016-06-24" @default.
- W1205325697 creator A5000859743 @default.
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- W1205325697 date "2016-01-01" @default.
- W1205325697 modified "2023-10-13" @default.
- W1205325697 title "Dynamic causal modelling of EEG and fMRI to characterize network architectures in a simple motor task" @default.
- W1205325697 cites W1517682131 @default.
- W1205325697 cites W1524318599 @default.
- W1205325697 cites W1540311052 @default.
- W1205325697 cites W1551536281 @default.
- W1205325697 cites W1591367364 @default.
- W1205325697 cites W1603307924 @default.
- W1205325697 cites W1732887939 @default.
- W1205325697 cites W1844619323 @default.
- W1205325697 cites W1854011899 @default.
- W1205325697 cites W1898894334 @default.
- W1205325697 cites W1944949903 @default.
- W1205325697 cites W1956761054 @default.
- W1205325697 cites W1965200637 @default.
- W1205325697 cites W1967064349 @default.
- W1205325697 cites W1967077913 @default.
- W1205325697 cites W1967934950 @default.
- W1205325697 cites W1969801285 @default.
- W1205325697 cites W1972525970 @default.
- W1205325697 cites W1978844490 @default.
- W1205325697 cites W1984587710 @default.
- W1205325697 cites W1991421001 @default.
- W1205325697 cites W1993174677 @default.
- W1205325697 cites W1993870554 @default.
- W1205325697 cites W1995767641 @default.
- W1205325697 cites W1996068683 @default.
- W1205325697 cites W1998151455 @default.
- W1205325697 cites W2001896030 @default.
- W1205325697 cites W2006621127 @default.
- W1205325697 cites W2006748433 @default.
- W1205325697 cites W2007884007 @default.
- W1205325697 cites W2008609531 @default.
- W1205325697 cites W2009031898 @default.
- W1205325697 cites W2013176407 @default.
- W1205325697 cites W2013685232 @default.
- W1205325697 cites W2015456912 @default.
- W1205325697 cites W2016371917 @default.
- W1205325697 cites W2016661105 @default.
- W1205325697 cites W2017562071 @default.
- W1205325697 cites W2029934372 @default.
- W1205325697 cites W2030807885 @default.
- W1205325697 cites W2032467910 @default.
- W1205325697 cites W2036633384 @default.
- W1205325697 cites W2040583781 @default.
- W1205325697 cites W2043301888 @default.
- W1205325697 cites W2043757388 @default.
- W1205325697 cites W2046980262 @default.
- W1205325697 cites W2049019336 @default.
- W1205325697 cites W2050103287 @default.
- W1205325697 cites W2052314238 @default.
- W1205325697 cites W2052834884 @default.
- W1205325697 cites W2053232757 @default.
- W1205325697 cites W2054225626 @default.
- W1205325697 cites W2059919805 @default.
- W1205325697 cites W2060563640 @default.
- W1205325697 cites W2061234590 @default.
- W1205325697 cites W2063842295 @default.
- W1205325697 cites W2064452374 @default.
- W1205325697 cites W2064979714 @default.
- W1205325697 cites W2066439376 @default.
- W1205325697 cites W2073128624 @default.
- W1205325697 cites W2077883484 @default.
- W1205325697 cites W2078377297 @default.
- W1205325697 cites W2079101166 @default.
- W1205325697 cites W2080823266 @default.
- W1205325697 cites W2086016692 @default.
- W1205325697 cites W2087017542 @default.
- W1205325697 cites W2088434677 @default.
- W1205325697 cites W2089250340 @default.
- W1205325697 cites W2090475450 @default.
- W1205325697 cites W2098406191 @default.
- W1205325697 cites W2103528520 @default.
- W1205325697 cites W2114104729 @default.
- W1205325697 cites W2114614491 @default.
- W1205325697 cites W2116308679 @default.
- W1205325697 cites W2117179240 @default.
- W1205325697 cites W2117294089 @default.
- W1205325697 cites W2117663940 @default.
- W1205325697 cites W2121775444 @default.
- W1205325697 cites W2128884192 @default.
- W1205325697 cites W2131634223 @default.
- W1205325697 cites W2135173838 @default.
- W1205325697 cites W2135396112 @default.
- W1205325697 cites W2138807694 @default.
- W1205325697 cites W2139037554 @default.
- W1205325697 cites W2142536013 @default.
- W1205325697 cites W2142875089 @default.
- W1205325697 cites W2147144756 @default.
- W1205325697 cites W2149421973 @default.