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• W120572143 abstract "Mitochondria are subcellular organelles with the most well-known and best-characterized function of adenosine triphosphate (ATP) production through oxidative phosphorylation (OXPHOS). Mitochondria play an important role in apoptosis, a fundamental biological process by which cells die in a programmed manner and are the strategic point in the cell death cascade. Alterations in respiratory activity and mitochondrial DNA (mtDNA) abnormalities appear to be a general feature of malignant cells. The presence of mtDNA mutations has been reported in most types of cancer. However, the functional consequences and clinical relevance of these mutations are not clear." @default.
• W120572143 created "2016-06-24" @default.
• W120572143 creator A5033464730 @default.
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• W120572143 date "2008-09-27" @default.
• W120572143 modified "2023-09-27" @default.
• W120572143 title "Mitochondrial DNA Mutations in Tumors" @default.
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• W120572143 doi "https://doi.org/10.1007/978-1-59745-435-3_9" @default.
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