Matches in SemOpenAlex for { <https://semopenalex.org/work/W1207455871> ?p ?o ?g. }
- W1207455871 abstract "Publisher Summary This chapter discusses the recent application of nuclear magnetic resonance (NMR) spectroscopy to the study of metabolism as it occurs in in situ and perfused organs and in cellular suspensions. Phosphorus-NMR (PNMR) spectroscopic studies have provided a wide variety of information on ex vivo brain tissue metabolism of the resting organ and more recently on the effects of hypoxia on a mammalian system. In brain metabolism, PNMR can be utilized to ascertain the intracellular pH and the bioenergetic status of the organ, and this can be correlated with changes in the function. A natural extension of this is the clinical application of NMR spectroscopy to study human, particularly neonate, cerebral function. Although the clinical applications of in vivo PNMR spectroscopy are far reaching, most basic research is still in the domain of the perfused animal model. Hydrogen-NMR (HNMR) spectroscopy is now being used to study the muscle preparations and extracts. H is more sensitive to the NMR experiment than P, and because of its ubiquitous distribution, a more complete range of tissue metabolites becomes accessible. In vivo PNMR spectroscopy has been applied determining the concentration and turnover of high-energy phosphates in the heart under various conditions. Recent progress in the study of liver metabolism by NMR spectroscopy has seen the use of carbon-13 surface coils. A recent review of the application of in vivo NMR spectroscopy to cancer covers metabolism by dispersed cells, excised tumors, and in vivo tumors. This diversity of available nuclides in tandem with further improvements in probe design and pulse sequences will, ensure the future of NMR spectroscopy as a viable technique for the study of biological systems." @default.
- W1207455871 created "2016-06-24" @default.
- W1207455871 creator A5083529624 @default.
- W1207455871 date "1985-01-01" @default.
- W1207455871 modified "2023-09-27" @default.
- W1207455871 title "Chapter 27. NMR Spectroscopy in Biological Systems" @default.
- W1207455871 cites W121781677 @default.
- W1207455871 cites W1494858583 @default.
- W1207455871 cites W1526255136 @default.
- W1207455871 cites W1533659084 @default.
- W1207455871 cites W1540937567 @default.
- W1207455871 cites W1550622639 @default.
- W1207455871 cites W1579207811 @default.
- W1207455871 cites W1598870595 @default.
- W1207455871 cites W1603552736 @default.
- W1207455871 cites W1603709949 @default.
- W1207455871 cites W1793595893 @default.
- W1207455871 cites W188059424 @default.
- W1207455871 cites W1954126887 @default.
- W1207455871 cites W1968491916 @default.
- W1207455871 cites W1968857087 @default.
- W1207455871 cites W1971800832 @default.
- W1207455871 cites W1972887240 @default.
- W1207455871 cites W1973447406 @default.
- W1207455871 cites W1974504658 @default.
- W1207455871 cites W1977323596 @default.
- W1207455871 cites W1977498271 @default.
- W1207455871 cites W1977923285 @default.
- W1207455871 cites W1979027357 @default.
- W1207455871 cites W1982107897 @default.
- W1207455871 cites W1983210051 @default.
- W1207455871 cites W1989169286 @default.
- W1207455871 cites W1992556292 @default.
- W1207455871 cites W1994073484 @default.
- W1207455871 cites W1994782117 @default.
- W1207455871 cites W1996407637 @default.
- W1207455871 cites W1996509361 @default.
- W1207455871 cites W1996691305 @default.
- W1207455871 cites W2000419942 @default.
- W1207455871 cites W2001242302 @default.
- W1207455871 cites W2007572107 @default.
- W1207455871 cites W2008871335 @default.
- W1207455871 cites W2010340643 @default.
- W1207455871 cites W2010425062 @default.
- W1207455871 cites W2010461181 @default.
- W1207455871 cites W2011646422 @default.
- W1207455871 cites W2014698537 @default.
- W1207455871 cites W2015118533 @default.
- W1207455871 cites W2016525048 @default.
- W1207455871 cites W2019832687 @default.
- W1207455871 cites W2020617485 @default.
- W1207455871 cites W2023833294 @default.
- W1207455871 cites W2025583682 @default.
- W1207455871 cites W2029407787 @default.
- W1207455871 cites W2031229650 @default.
- W1207455871 cites W2033616923 @default.
- W1207455871 cites W2035737248 @default.
- W1207455871 cites W2038713125 @default.
- W1207455871 cites W2044314143 @default.
- W1207455871 cites W2046408314 @default.
- W1207455871 cites W2047202942 @default.
- W1207455871 cites W2049822517 @default.
- W1207455871 cites W2052563473 @default.
- W1207455871 cites W2053702939 @default.
- W1207455871 cites W2054007029 @default.
- W1207455871 cites W2061496400 @default.
- W1207455871 cites W2061928885 @default.
- W1207455871 cites W2063871697 @default.
- W1207455871 cites W2064972745 @default.
- W1207455871 cites W2065924760 @default.
- W1207455871 cites W2071106953 @default.
- W1207455871 cites W2085586114 @default.
- W1207455871 cites W2086170809 @default.
- W1207455871 cites W2087232199 @default.
- W1207455871 cites W2088388161 @default.
- W1207455871 cites W2089873002 @default.
- W1207455871 cites W2092959264 @default.
- W1207455871 cites W2094351270 @default.
- W1207455871 cites W2106455632 @default.
- W1207455871 cites W2109338044 @default.
- W1207455871 cites W2117025288 @default.
- W1207455871 cites W2133144313 @default.
- W1207455871 cites W2135487258 @default.
- W1207455871 cites W2141639503 @default.
- W1207455871 cites W2145642021 @default.
- W1207455871 cites W2146575455 @default.
- W1207455871 cites W2146586334 @default.
- W1207455871 cites W2151920311 @default.
- W1207455871 cites W2156556283 @default.
- W1207455871 cites W2159170186 @default.
- W1207455871 cites W2171554775 @default.
- W1207455871 cites W2250528317 @default.
- W1207455871 cites W2258695173 @default.
- W1207455871 cites W2263057313 @default.
- W1207455871 cites W2301552481 @default.
- W1207455871 cites W2313835802 @default.
- W1207455871 cites W2395040797 @default.
- W1207455871 cites W2396148784 @default.
- W1207455871 cites W2396263467 @default.
- W1207455871 cites W2406124711 @default.