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- W1208484503 abstract "Publisher Summary This chapter outlines the evolutionary history of the herpesviruses that form a group of large DNA viruses that are widely distributed in nature. The range of disease associations and biological characteristics found across this group is substantial. Historically, herpesviruses were defined by their characteristic virion architecture: an icosahedral capsid of diameter near 125 nm and with 162 capsomeric spikes embedded in an amorphous proteinaceous matrix (tegument), and enveloped with a lipid membrane carrying external glycoproteins to give an overall diameter of nearly 215 nm. The chapter describes genome sequences and encoded protein sequences to discern processes that have occurred during evolution and constructs a phylogenetic description of the mammalian and avian viruses. The DNA genomes are heterogeneous in terms of size, base composition, gene content, and organization. The overall scheme of herpesvirus evolution elaborates the development of herpesviruses in much the same timeframe as that of the vertebrates." @default.
- W1208484503 created "2016-06-24" @default.
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- W1208484503 date "1999-01-01" @default.
- W1208484503 modified "2023-10-14" @default.
- W1208484503 title "The Molecular Evolutionary History of the Herpesviruses" @default.
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- W1208484503 doi "https://doi.org/10.1016/b978-012220360-2/50018-0" @default.
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