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- W12117631 abstract "Kupffer cells (KC), a kind of nonparenchymal cells and defenders in the liver, release various chemical mediators to induce liver injury, and play an important role in many pathologic changes of the liver. Hepatic fibrosis is the common pathologic process of varied chronic liver diseases, and it is also a “transfer station” for many chronic liver diseases lapsing to cirrhosis. As important influencing factors, cytokines secreted by KC are involved in the occurrence and progression of hepatic fibrosis. Therefore, lucubrating the role and mechanism of KC in the progression of hepatic fibrosis, and investigating the KC-related therapeutic strategies of antifibrosis have practical significances for the prevention and treatment of liver injury and the raise of patients’ survival rates in clinical practice." @default.
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- W12117631 date "2008-01-01" @default.
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- W12117631 title "Role of Kupffer cells in hepatic fibrosis" @default.
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- W12117631 doi "https://doi.org/10.11569/wcjd.v16.i26.2959" @default.
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