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• W1219808221 abstract "This chapter highlights calcium tracer exchange in the rods of excised retinas. Calcium is the required intracellular transmitter that mediates receptor excitation. Whether measured within intact receptors or in cell fragments, calcium releases are either undetectable or too small in terms of their magnitude. The specific structure of the outer segment and the distribution of its total calcium content must be considered before the unidirectional flux across disk membranes can be calculated from the tracer-exchange data. The chapter discusses the equivalent model for tracer exchange in rod outer segments (ROSs)—two compartments in series with a reservoir. However, recent measurements with tracer exchange indicate that even within intact receptors, calcium uptake by disks is too slow to be compatible with the calcium hypothesis." @default.
• W1219808221 created "2016-06-24" @default.
• W1219808221 creator A5044494552 @default.
• W1219808221 date "1981-01-01" @default.
• W1219808221 modified "2023-09-27" @default.
• W1219808221 title "Chapter 16 Calcium Tracer Exchange in the Rods of Excised Retinas" @default.
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• W1219808221 doi "https://doi.org/10.1016/s0070-2161(08)60507-9" @default.
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