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- W1222156931 abstract "Transcranial Direct Current Stimulation (tDCS) has been recently proposed as a treatment for treatment-resistant auditory verbal hallucinations in patients with schizophrenia [ [1] Mondino M. Brunelin J. Palm U. Brunoni A.R. Poulet E. Fecteau S. Transcranial direct current stimulation for the treatment of refractory symptoms of schizophrenia. Current evidence and future directions. Curr Pharm Des. 2015; 21: 3373-3383 Crossref PubMed Scopus (54) Google Scholar ]. In these studies, 10 sessions of tDCS were delivered twice a day during 5 days with the cathode placed over the left temporo-parietal junction coupled with the anode placed over the left prefrontal region. Despite promising results (−30% of auditory hallucinations), evidence suggested that some patients with schizophrenia failed to respond to this tDCS regimen [ [1] Mondino M. Brunelin J. Palm U. Brunoni A.R. Poulet E. Fecteau S. Transcranial direct current stimulation for the treatment of refractory symptoms of schizophrenia. Current evidence and future directions. Curr Pharm Des. 2015; 21: 3373-3383 Crossref PubMed Scopus (54) Google Scholar ] and the knowledge regarding predictive markers of response and mechanisms of action is still sparse. Neurophysiological studies however indicate that tDCS induces changes in neural plasticity via LTP-LTD like phenomena [ [2] Monte-Silva K. Kuo M.F. Hessenthaler S. et al. Induction of late LTP-like plasticity in the human motor cortex by repeated non-invasive brain stimulation. Brain Stimul. 2013; 6: 424-432 Abstract Full Text Full Text PDF PubMed Scopus (552) Google Scholar ]." @default.
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- W1222156931 date "2015-11-01" @default.
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- W1222156931 title "Nicotine Smoking Prevents the Effects of Frontotemporal Transcranial Direct Current Stimulation (tDCS) in Hallucinating Patients With Schizophrenia" @default.
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