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- W122607316 abstract "L-tryptophan (Trp), an essential amino acid which is the precursor for serotonin (5-HT), was administered orally as an adjunctive therapy in three patients with chronic disabling pain of widely divergent etiologies All three patients had relatively stable, consistently severe pain and had been taking narcotic medications. Each patient given oral Trp in the dosage 4 g twice a day, experienced a reduction in pain and voluntarily reduced narcotic doses by at least one-third. Although there were some side effects of nausea and vomiting, this did not cause any patient to discontinue taking Trp permanently. Each patient also increased daily activities during the course of Trp treatment. All have continued these positive responses for 3 to 6 months with no signs of tolerance noted." @default.
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- W122607316 date "1980-01-01" @default.
- W122607316 modified "2023-09-25" @default.
- W122607316 title "ORAL TRYPTOPHAN AS A POTENTIAL ADJUNCTIVE THERAPY IN CHRONIC PAIN PATIENTS" @default.
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- W122607316 doi "https://doi.org/10.1016/b978-0-08-025488-3.50096-9" @default.
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