Matches in SemOpenAlex for { <https://semopenalex.org/work/W123459165> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W123459165 endingPage "134" @default.
- W123459165 startingPage "115" @default.
- W123459165 abstract "This study describes the pathogenesis of the Ebola-Reston (EBO-R) subtype of Ebola virus for experimentally infected cynomolgus monkeys. The disease course of EBO-R in macaques was very similar to human disease and to experimental diseases in macaques following EBO-Zaire and EBO-Sudan infections. Cynomolgus monkeys infected with EBO-R in this experiment developed anorexia, occasional nasal discharge, and splenomegaly, petechial facial hemorrhages and severe subcutaneous hemorrhages in venipuncture sites, similar to human Ebola fever. Five of the six EBO-R infected monkeys died, 8 to 14 days after inoculation. One survived and developed high titered neutralizing antibodies specific for EBO-R. The five acutely ill monkeys shed infectious virus in various bodily secretions. Further, abundant virus was visualized in alveolar interstitial cells and free in the alveoli suggesting the potential for generating infectious aerosols. Thus, taking precautions against aerosol exposures to filovirus infected primates, including humans, seems prudent. This experiment demonstrated that EBO-R was lethal for macaques and was capable of initiating and sustaining the monkey epizootic. Further investigation of this animal model should facilitate development of effective immunization, treatment, and control strategies for Ebola hemorrhagic fever." @default.
- W123459165 created "2016-06-24" @default.
- W123459165 creator A5004889377 @default.
- W123459165 creator A5007410602 @default.
- W123459165 creator A5031262013 @default.
- W123459165 creator A5038614700 @default.
- W123459165 creator A5039637495 @default.
- W123459165 creator A5061065988 @default.
- W123459165 date "1996-01-01" @default.
- W123459165 modified "2023-10-14" @default.
- W123459165 title "Experimental infection of cynomolgus macaques with Ebola-Reston filoviruses from the 1989–1990 U.S. epizootic" @default.
- W123459165 cites W1238725244 @default.
- W123459165 cites W1853748609 @default.
- W123459165 cites W1863223069 @default.
- W123459165 cites W1958404020 @default.
- W123459165 cites W1972412663 @default.
- W123459165 cites W1981799010 @default.
- W123459165 cites W1983587760 @default.
- W123459165 cites W1993048073 @default.
- W123459165 cites W2020081738 @default.
- W123459165 cites W2022675863 @default.
- W123459165 cites W2033815173 @default.
- W123459165 cites W2054182181 @default.
- W123459165 cites W2071645211 @default.
- W123459165 cites W2077257157 @default.
- W123459165 cites W2084944660 @default.
- W123459165 cites W2133600490 @default.
- W123459165 cites W2142252152 @default.
- W123459165 cites W2143487768 @default.
- W123459165 cites W4240404813 @default.
- W123459165 doi "https://doi.org/10.1007/978-3-7091-7482-1_11" @default.
- W123459165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8800793" @default.
- W123459165 hasPublicationYear "1996" @default.
- W123459165 type Work @default.
- W123459165 sameAs 123459165 @default.
- W123459165 citedByCount "45" @default.
- W123459165 countsByYear W1234591652012 @default.
- W123459165 countsByYear W1234591652013 @default.
- W123459165 countsByYear W1234591652014 @default.
- W123459165 countsByYear W1234591652015 @default.
- W123459165 countsByYear W1234591652016 @default.
- W123459165 countsByYear W1234591652017 @default.
- W123459165 countsByYear W1234591652018 @default.
- W123459165 countsByYear W1234591652019 @default.
- W123459165 countsByYear W1234591652020 @default.
- W123459165 countsByYear W1234591652022 @default.
- W123459165 crossrefType "book-chapter" @default.
- W123459165 hasAuthorship W123459165A5004889377 @default.
- W123459165 hasAuthorship W123459165A5007410602 @default.
- W123459165 hasAuthorship W123459165A5031262013 @default.
- W123459165 hasAuthorship W123459165A5038614700 @default.
- W123459165 hasAuthorship W123459165A5039637495 @default.
- W123459165 hasAuthorship W123459165A5061065988 @default.
- W123459165 hasConcept C142724271 @default.
- W123459165 hasConcept C159047783 @default.
- W123459165 hasConcept C203014093 @default.
- W123459165 hasConcept C2522874641 @default.
- W123459165 hasConcept C2777469322 @default.
- W123459165 hasConcept C2778511750 @default.
- W123459165 hasConcept C2779134260 @default.
- W123459165 hasConcept C2909623084 @default.
- W123459165 hasConcept C2910344980 @default.
- W123459165 hasConcept C524204448 @default.
- W123459165 hasConcept C71924100 @default.
- W123459165 hasConcept C86803240 @default.
- W123459165 hasConceptScore W123459165C142724271 @default.
- W123459165 hasConceptScore W123459165C159047783 @default.
- W123459165 hasConceptScore W123459165C203014093 @default.
- W123459165 hasConceptScore W123459165C2522874641 @default.
- W123459165 hasConceptScore W123459165C2777469322 @default.
- W123459165 hasConceptScore W123459165C2778511750 @default.
- W123459165 hasConceptScore W123459165C2779134260 @default.
- W123459165 hasConceptScore W123459165C2909623084 @default.
- W123459165 hasConceptScore W123459165C2910344980 @default.
- W123459165 hasConceptScore W123459165C524204448 @default.
- W123459165 hasConceptScore W123459165C71924100 @default.
- W123459165 hasConceptScore W123459165C86803240 @default.
- W123459165 hasLocation W1234591651 @default.
- W123459165 hasLocation W1234591652 @default.
- W123459165 hasOpenAccess W123459165 @default.
- W123459165 hasPrimaryLocation W1234591651 @default.
- W123459165 hasRelatedWork W123459165 @default.
- W123459165 hasRelatedWork W2077257157 @default.
- W123459165 hasRelatedWork W2080638283 @default.
- W123459165 hasRelatedWork W2115174286 @default.
- W123459165 hasRelatedWork W2178305569 @default.
- W123459165 hasRelatedWork W2619904095 @default.
- W123459165 hasRelatedWork W2772479624 @default.
- W123459165 hasRelatedWork W2790700860 @default.
- W123459165 hasRelatedWork W2883430655 @default.
- W123459165 hasRelatedWork W3151280873 @default.
- W123459165 isParatext "false" @default.
- W123459165 isRetracted "false" @default.
- W123459165 magId "123459165" @default.
- W123459165 workType "book-chapter" @default.