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• W1237762235 endingPage "2681" @default.
• W1237762235 startingPage "2669" @default.
• W1237762235 abstract "Viruses successfully infect host cells by initially binding to the surfaces of the cells, followed by an intricate entry process. As multifunctional heterodimeric cell-surface receptor molecules, integrins have been shown to usefully serve as entry receptors for a plethora of viruses. However, the exact role(s) of integrins in viral pathogen internalization has yet to be elaborately described. Notably, several viruses harbor integrin-recognition motifs displayed on viral envelope/capsid-associated proteins. The most common of these motifs is the minimal peptide sequence for binding integrins, RGD (Arg-Gly-Asp), which is known for its role in virus infection via its ability to interact with over half of the more than 20 known integrins. Not all virus-integrin interactions are RGD-dependent, however. Non-RGD-binding integrins have also been shown to effectively promote virus entry and infection as well. Such virus-integrin binding is shown to facilitate adhesion, cytoskeleton rearrangement, integrin activation, and increased intracellular signaling. Also, we have attempted to discuss the role of carbohydrate moieties in virus interactions with receptor-like host cell surface integrins that drive the process of internalization. As much as possible, this article examines the published literature regarding the role of integrins in terms of virus infection and virus-encoded glycosylated proteins that mediate interactions with integrins, and it explores the idea of targeting these receptors as a therapeutic treatment option." @default.
• W1237762235 created "2016-06-24" @default.
• W1237762235 creator A5049994482 @default.
• W1237762235 creator A5050515421 @default.
• W1237762235 creator A5055119130 @default.
• W1237762235 creator A5069744624 @default.
• W1237762235 creator A5071016461 @default.
• W1237762235 creator A5088177794 @default.
• W1237762235 date "2015-09-01" @default.
• W1237762235 modified "2023-10-02" @default.
• W1237762235 title "Beyond RGD: virus interactions with integrins" @default.
• W1237762235 cites W1488128764 @default.
• W1237762235 cites W1505196125 @default.
• W1237762235 cites W1532885297 @default.
• W1237762235 cites W1533970263 @default.
• W1237762235 cites W1543232849 @default.
• W1237762235 cites W1576773659 @default.
• W1237762235 cites W1576880857 @default.
• W1237762235 cites W1597577233 @default.
• W1237762235 cites W1600560134 @default.
• W1237762235 cites W1601996378 @default.
• W1237762235 cites W1603226294 @default.
• W1237762235 cites W1610515357 @default.
• W1237762235 cites W1682346320 @default.
• W1237762235 cites W171495812 @default.
• W1237762235 cites W1774068000 @default.
• W1237762235 cites W184174936 @default.
• W1237762235 cites W1877406376 @default.
• W1237762235 cites W188511696 @default.
• W1237762235 cites W1895561430 @default.
• W1237762235 cites W1938388466 @default.
• W1237762235 cites W1963377338 @default.
• W1237762235 cites W1966022051 @default.
• W1237762235 cites W1966564357 @default.
• W1237762235 cites W1967111434 @default.
• W1237762235 cites W1968443620 @default.
• W1237762235 cites W1969342647 @default.
• W1237762235 cites W1969432457 @default.
• W1237762235 cites W1970483666 @default.
• W1237762235 cites W1970900822 @default.
• W1237762235 cites W1970923523 @default.
• W1237762235 cites W1972470306 @default.
• W1237762235 cites W1972975850 @default.
• W1237762235 cites W1976704214 @default.
• W1237762235 cites W1976844592 @default.
• W1237762235 cites W1977368737 @default.
• W1237762235 cites W1979147695 @default.
• W1237762235 cites W1982398946 @default.
• W1237762235 cites W1982798128 @default.
• W1237762235 cites W1986159739 @default.
• W1237762235 cites W1987210689 @default.
• W1237762235 cites W1992223490 @default.
• W1237762235 cites W1995061843 @default.
• W1237762235 cites W1998892400 @default.
• W1237762235 cites W1999442372 @default.
• W1237762235 cites W2001339111 @default.
• W1237762235 cites W2001371234 @default.
• W1237762235 cites W2002263537 @default.
• W1237762235 cites W2002942987 @default.
• W1237762235 cites W2003040183 @default.
• W1237762235 cites W2003955696 @default.
• W1237762235 cites W2006040964 @default.
• W1237762235 cites W2006446093 @default.
• W1237762235 cites W2006682991 @default.
• W1237762235 cites W2007639993 @default.
• W1237762235 cites W2007755785 @default.
• W1237762235 cites W2010320204 @default.
• W1237762235 cites W2012994594 @default.
• W1237762235 cites W2013381560 @default.
• W1237762235 cites W2014485319 @default.
• W1237762235 cites W2015775910 @default.
• W1237762235 cites W2016171668 @default.
• W1237762235 cites W2021061361 @default.
• W1237762235 cites W2021109304 @default.
• W1237762235 cites W2021275530 @default.
• W1237762235 cites W2022652595 @default.
• W1237762235 cites W2023133790 @default.
• W1237762235 cites W2023588767 @default.
• W1237762235 cites W2023663057 @default.
• W1237762235 cites W2024600235 @default.
• W1237762235 cites W2025494340 @default.
• W1237762235 cites W2026184890 @default.
• W1237762235 cites W2028465837 @default.
• W1237762235 cites W2029570876 @default.
• W1237762235 cites W2029677015 @default.
• W1237762235 cites W2030604587 @default.
• W1237762235 cites W2035809865 @default.
• W1237762235 cites W2038413195 @default.
• W1237762235 cites W2045377853 @default.
• W1237762235 cites W2046207936 @default.
• W1237762235 cites W2046488302 @default.
• W1237762235 cites W2047157488 @default.
• W1237762235 cites W2047204461 @default.
• W1237762235 cites W2047876133 @default.
• W1237762235 cites W2048846997 @default.
• W1237762235 cites W2048973430 @default.
• W1237762235 cites W2049556477 @default.
• W1237762235 cites W2050446286 @default.

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