FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W123841818> ?p ?o ?g. }

• W123841818 endingPage "1287" @default.
• W123841818 startingPage "1280" @default.
• W123841818 abstract "Back to table of contents Previous article Next article No AccessCognition and white matter hyperintensities in older depressed patientsPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.153.10.1280AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: The authors compared amounts of white matter hyperintensity in late- and early-onset depressed patients and never-depressed older subjects, compared neuropsychological function in these groups, and investigated the association between white matter hyperintensities and cognitive function in depression. METHOD: Sixty currently depressed patients whose first depression occurred after age 50 years, 35 depressed patients over age 50 whose first depression occurred before age 35, and 165 nonpsychiatrically ill subjects over age 50 underwent magnetic resonance imaging (MRI) and neuropsychological evaluation. Areas of white matter hyperintensity were measured from MRI images. RESULTS: The late-onset patients had more white matter hyperintensity than either of the other groups. Compared to the nondepressed subjects, the patients had significantly lower scores in the cognitive domains of nonverbal intelligence, nonverbal memory, constructional ability, executive ability, and information processing speed. The cognitive abnormalities were mostly confined to the late-onset patients, and the presence of a large amount of white matter hyperintensity was associated with significantly poorer executive skills. However, most of the scores were not in the significantly impaired range. CONCLUSIONS: Large amounts of white matter hyperintensity are more frequent in patients with late-onsetdepression than in elderly subjects with early- onset or no depression. Both late- and early-onset elderly depressed patients show mild decrements in some right hemisphere cognitive skills; the late-onset subjects also show deterioration in information processing speed and executive functions. Patients with large amounts of white matter hyperintensity have significantly poorer executive function. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byHeterogenous Subtypes of Late-Life Depression and Their Cognitive Patterns: A Latent Class Analysis6 July 2022 | Frontiers in Psychiatry, Vol. 13Brain-based mechanisms of late-life depression: Implications for novel interventionsSeminars in Cell & Developmental Biology, Vol. 116The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life DepressionJournal of Alzheimer's Disease, Vol. 58Study of neuropsychological deficits in late onset depressionAsian Journal of Psychiatry, Vol. 54Comparison of cognitive function between early- and late-onset late-life depression in remissionPsychiatry Research, Vol. 290Vascular depression for radiology: A review of the construct, methodology, and diagnosisWorld Journal of Radiology, Vol. 12, No. 5An inverse relationship between cortical plasticity and cognitive inhibition in late-life depression9 May 2019 | Neuropsychopharmacology, Vol. 44, No. 9International Journal of Geriatric Psychiatry, Vol. 34, No. 1Journal of Affective Disorders, Vol. 250NeuroImage: Clinical, Vol. 23Frontiers in Aging Neuroscience, Vol. 10Hirnstrukturelle und funktionelle Bildgebung2 June 2017The American Journal of Geriatric Psychiatry, Vol. 25, No. 7Disrupted orbitomedial prefrontal limbic network in individuals with later-life depressionJournal of Affective Disorders, Vol. 204Late-onset depressive symptoms increase the risk of dementia in small vessel disease12 August 2016 | Neurology, Vol. 87, No. 11International Journal of Geriatric Psychiatry, Vol. 31, No. 6International Journal of Geriatric Psychiatry, Vol. 31, No. 11Moving Beyond Mood: Is it Time to Recommend Cognitive Training for Depression in Older Adults?2 August 2016Revista Española de Geriatría y Gerontología, Vol. 51, No. 2International Journal of Geriatric Psychiatry, Vol. 30, No. 11, Vol. 8The American Journal of Geriatric Psychiatry, Vol. 23, No. 5International Journal of Geriatric Psychiatry, Vol. 29, No. 5General Hospital Psychiatry, Vol. 36, No. 4The American Journal of Geriatric Psychiatry, Vol. 22, No. 12The American Journal of Geriatric Psychiatry, Vol. 22, No. 12Journal of Clinical and Experimental Neuropsychology, Vol. 36, No. 4Cognition as a therapeutic target in late-life depression: Potential for nicotinic therapeuticsBiochemical Pharmacology, Vol. 86, No. 8The vascular depression hypothesis: mechanisms linking vascular disease with depression26 February 2013 | Molecular Psychiatry, Vol. 18, No. 9Little Evidence for the Graphical Markers of Depression1 August 2013 | Perceptual and Motor Skills, Vol. 117, No. 1International Journal of Geriatric Psychiatry, Vol. 28, No. 4Neuroscience & Biobehavioral Reviews, Vol. 37, No. 10Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 43Psychiatric Clinics of North America, Vol. 36, No. 4Current Opinion in Neurology, Vol. 26, No. 6Journal of Neurology, Neurosurgery & Psychiatry, Vol. 84, No. 11A Correlation Analysis between the Location of White Matter Hyperintensities and Cognitive Functions in Korean Vascular Depression PatientsJournal of Korean Neuropsychiatric Association, Vol. 52, No. 4American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Vol. 159B, No. 5International Journal of Geriatric Psychiatry, Vol. 27, No. 8Archives of Gerontology and Geriatrics, Vol. 55, No. 2Journal of Affective Disorders, Vol. 136, No. 3Progress in Neurobiology, Vol. 98, No. 1Psychiatry Research: Neuroimaging, Vol. 201, No. 2Psychiatry Research: Neuroimaging, Vol. 203, No. 2-3Structural Neuroimaging Studies in Major Depressive DisorderArchives of General Psychiatry, Vol. 68, No. 7International Journal of Geriatric Psychiatry, Vol. 26, No. 5International Journal of Geriatric Psychiatry, Vol. 26, No. 6Journal of Affective Disorders, Vol. 135, No. 1-3The American Journal of Geriatric Psychiatry, Vol. 19, No. 2The American Journal of Geriatric Psychiatry, Vol. 19, No. 10International Review of Psychiatry, Vol. 23, No. 5Journal of Aging Research, Vol. 2011Structural imaging of major depressionCortical and Subcortical Abnormalities in Late-Onset Depression With History of Suicide Attempts Investigated With MRI and Voxel-Based Morphometry29 April 2010 | Journal of Geriatric Psychiatry and Neurology, Vol. 23, No. 3International Journal of Geriatric PsychiatryAging Clinical and Experimental Research, Vol. 22, No. 2Journal of Affective Disorders, Vol. 126, No. 3International Psychogeriatrics, Vol. 22, No. 3Archives of Clinical Neuropsychology, Vol. 25, No. 2The American Journal of Geriatric Psychiatry, Vol. 18, No. 2Neuropathology and Applied Neurobiology, Vol. 36, No. 7International Journal of Geriatric Psychiatry, Vol. 24, No. 8International Journal of Geriatric Psychiatry, Vol. 25, No. 10Brain Imaging and Behavior, Vol. 3, No. 4Biological Psychiatry, Vol. 66, No. 9Journal of Affective Disorders, Vol. 115, No. 1-2Psychiatry Research: Neuroimaging, Vol. 171, No. 1Psychological Medicine, Vol. 39, No. 5International Psychogeriatrics, Vol. 21, No. 05The American Journal of Geriatric Psychiatry, Vol. 17, No. 1The American Journal of Geriatric Psychiatry, Vol. 17, No. 10Pathways linking late-life depression to persistent cognitive impairment and dementia1 April 2022 | Dialogues in Clinical Neuroscience, Vol. 10, No. 3International Journal of Geriatric Psychiatry, Vol. 23, No. 4International Journal of Geriatric Psychiatry, Vol. 23, No. 6International Journal of Geriatric Psychiatry, Vol. 23, No. 8Biological Psychiatry, Vol. 64, No. 6Journal of Affective Disorders, Vol. 106, No. 1-2Journal of Affective Disorders, Vol. 111, No. 1Aging & Mental Health, Vol. 12, No. 1Journal of Clinical and Experimental Neuropsychology, Vol. 30, No. 2The American Journal of Geriatric Psychiatry, Vol. 16, No. 4Acta Psychiatrica Scandinavica, Vol. 118, No. 5Distinguishing Between Depression and Dementia in Older Persons: Neuropsychological and Neuropathological Correlates29 June 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 20, No. 4White matter integrity of the whole brain is disrupted in first-episode remitted geriatric depressionNeuroReport, Vol. 18, No. 17Behavioral Sciences & the Law, Vol. 25, No. 3International Journal of Geriatric Psychiatry, Vol. 22, No. 1International Journal of Geriatric Psychiatry, Vol. 22, No. 4International Journal of Geriatric Psychiatry, Vol. 22, No. 2European Archives of Psychiatry and Clinical Neuroscience, Vol. 257, No. 8L'Encéphale, Vol. 33, No. 1Archives of Gerontology and Geriatrics, Vol. 44Biological Psychiatry, Vol. 61, No. 8Journal of Affective Disorders, Vol. 104, No. 1-3Psychological Medicine, Vol. 37, No. 12Neuropsychopharmacology, Vol. 32, No. 9The American Journal of Geriatric Psychiatry, Vol. 15, No. 7Bipolar Disorders, Vol. 9, No. 8Dementia and Geriatric Cognitive Disorders, Vol. 23, No. 4Rôle du stress dans la dépression à début tardif et précoce chez le sujet âgéL'Encéphale, Vol. 32, No. 6International Journal of Geriatric Psychiatry, Vol. 21, No. 1International Journal of Geriatric Psychiatry, Vol. 21, No. 2International Journal of Geriatric Psychiatry, Vol. 21, No. 4, Vol. 111Der Nervenarzt, Vol. 77, No. 10Biological Psychiatry, Vol. 60, No. 12Biological Psychiatry, Vol. 60, No. 12Journal of Affective Disorders, Vol. 91, No. 2-3International Review of Psychiatry, Vol. 18, No. 5Journal of Clinical and Experimental Neuropsychology, Vol. 28, No. 4The American Journal of Geriatric Psychiatry, Vol. 14, No. 7The American Journal of Geriatric Psychiatry, Vol. 14, No. 5Dementia and Geriatric Cognitive Disorders, Vol. 21, No. 1Brain MRI white matter hyperintensities and one-carbon cycle metabolism in non-geriatric outpatients with major depressive disorder (Part I)Psychiatry Research: Neuroimaging, Vol. 140, No. 3Depressive Symptoms and Carotid Artery Intima-Media Thickness in Young Adults: The Cardiovascular Risk in Young Finns StudyPsychosomatic Medicine, Vol. 67, No. 4Hypofrontality and microvascular dysregulation in remitted late-onset depression assessed by functional near-infrared spectroscopyNeuroImage, Vol. 26, No. 1Geriatric Depression29 January 2008Journal of Psychiatric Research, Vol. 39, No. 2Journal of Psychiatric Research, Vol. 39, No. 3The American Journal of Geriatric Psychiatry, Vol. 13, No. 1The American Journal of Geriatric Psychiatry, Vol. 13, No. 2Localizing Gray Matter Deficits in Late-Onset Depression Using Computational Cortical Pattern Matching MethodsMartina Ballmaier, M.D., Anand Kumar, M.D., Paul M. Thompson, Ph.D., Katherine L. Narr, Ph.D., Helen Lavretsky, M.D., Laverne Estanol, B.S., Heather DeLuca, B.S., and Arthur W. Toga, Ph.D.28 January 2015 | American Journal of Psychiatry, Vol. 161, No. 11Late-Life Depression and Microstructural Abnormalities in Dorsolateral Prefrontal Cortex White MatterWarren D. Taylor, M.D., James R. MacFall, Ph.D., Martha E. Payne, M.P.H., R.D., Douglas R. McQuoid, B.S., James M. Provenzale, M.D., David C. Steffens, M.D., M.H.S., and K. Ranga Rama Krishnan, M.D.1 July 2004 | American Journal of Psychiatry, Vol. 161, No. 7Depression Comorbidity With COPDPsychiatric Annals, Vol. 34, No. 4Vascular depression: Recent advancesCurrent Psychosis and Therapeutics Reports, Vol. 2, No. 1Aging Clinical and Experimental Research, Vol. 16, No. 3Journal of Affective Disorders, Vol. 78, No. 3Journal of Affective Disorders, Vol. 81, No. 1Journal of the Neurological Sciences, Vol. 226, No. 1-2Depressive Störungen im Alter - Symptombesonderheiten und körperliche ErkrankungenZeitschrift für Gerontopsychologie & -psychiatrie, Vol. 17, No. 4Neuropsychopharmacology, Vol. 29, No. 12The American Journal of Geriatric Psychiatry, Vol. 12, No. 1The American Journal of Geriatric Psychiatry, Vol. 12, No. 2The American Journal of Geriatric Psychiatry, Vol. 12, No. 4Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 43, No. 6Dementia and Geriatric Cognitive Disorders, Vol. 18, No. 3-4Depression in Alzheimer’s disease: heterogeneity and related issuesBiological Psychiatry, Vol. 54, No. 3Deep white matter hyperintensities in patients with bipolar depression, unipolar depression and age-matched control subjects12 February 2003 | Bipolar Disorders, Vol. 5, No. 1The Limbic BrainJOHANNES PANTEL, M.D., 1 January 2003 | American Journal of Psychiatry, Vol. 160, No. 1Cognitive Neuroscience of EmotionPETER V. RABINS, M.D., M.P.H., 1 January 2003 | American Journal of Psychiatry, Vol. 160, No. 1Depression in Late Life, 3rd ed.GEORGE S. ALEXOPOULOS, M.D., 1 January 2003 | American Journal of Psychiatry, Vol. 160, No. 1International Journal of Geriatric Psychiatry, Vol. 18, No. 6International Journal of Geriatric Psychiatry, Vol. 18, No. 7Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 27, No. 3The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Vol. 58, No. 12Executive Dysfunction in Geriatric DepressionKathryn A. Lockwood, Ph.D., George S. Alexopoulos, M.D., and Wilfred G. van Gorp, Ph.D.1 July 2002 | American Journal of Psychiatry, Vol. 159, No. 7International Journal of Geriatric Psychiatry, Vol. 17, No. 11Biological Psychiatry, Vol. 52, No. 6Journal of Psychosomatic Research, Vol. 53, No. 2Journal of the Neurological Sciences, Vol. 203-204CNS Spectrums, Vol. 7, No. 10CNS Spectrums, Vol. 7, No. 10CNS Spectrums, Vol. 7, No. 2The American Journal of Geriatric Psychiatry, Vol. 10, No. 1The American Journal of Geriatric Psychiatry, Vol. 10, No. 5The American Journal of Geriatric Psychiatry, Vol. 10, No. 6Journal of Psychiatric Practice, Vol. 8, No. 3British Journal of Psychiatry, Vol. 180, No. 4Brain aging research at the close of the 20th century: from bench to bedside1 April 2022 | Dialogues in Clinical Neuroscience, Vol. 3, No. 3New Concepts for Prevention and Treatment of Late-Life DepressionGeorge S. Alexopoulos, M.D.1 June 2001 | American Journal of Psychiatry, Vol. 158, No. 6International Journal of Geriatric Psychiatry, Vol. 16, No. 3International Journal of Geriatric Psychiatry, Vol. 16, No. 12Mechanisms of Ageing and Development, Vol. 122, No. 16Journal of Affective Disorders, Vol. 66, No. 2-3The American Journal of Geriatric Psychiatry, Vol. 9, No. 1The American Journal of Geriatric Psychiatry, Vol. 9, No. 3Psychogeriatrics, Vol. 1, No. 3British Journal of Psychiatry, Vol. 178, No. 3British Journal of Psychiatry, Vol. 178, No. S41Arquivos de Neuro-Psiquiatria, Vol. 59, No. 3BThe World Journal of Biological Psychiatry, Vol. 2, No. 2Changes in Cognitive Functioning Following Treatment of Late-Life DepressionMeryl A. Butters, Ph.D., James T. Becker, Ph.D., Robert D. Nebes, Ph.D., Michelle D. Zmuda, B.S., Benoit H. Mulsant, M.D., Bruce G. Pollock, M.D., Ph.D., and Charles F. ReynoldsIII, M.D.1 December 2000 | American Journal of Psychiatry, Vol. 157, No. 12Symptoms of striatofrontal dysfunction contribute to disability in geriatric depression1 January 2000 | International Journal of Geriatric Psychiatry, Vol. 15, No. 11International Journal of Geriatric Psychiatry, Vol. 15, No. 12ReferencesEpidemiologia e Psichiatria Sociale, Vol. 9, No. 2The American Journal of Geriatric Psychiatry, Vol. 8, No. 1The American Journal of Geriatric Psychiatry, Vol. 8, No. 3The American Journal of Geriatric Psychiatry, Vol. 8, No. 3Neuroanatomic Substrates of Late-Life Mental Disorders29 June 2016 | Journal of Geriatric Psychiatry and Neurology, Vol. 12, No. 3Neuropsychological Functioning and MRI Signal Hyperintensities in Geriatric DepressionElisse Kramer-Ginsberg, Ph.D., Blaine S. Greenwald, M.D., K. Ranga Rama Krishnan, M.D., Bruce Christiansen, Ph.D., Jian Hu, M.D., Manzar Ashtari, M.D., Mahendra Patel, M.D., and Simcha Pollack, Ph.D.1 March 1999 | American Journal of Psychiatry, Vol. 156, No. 3Current Psychiatry Reports, Vol. 1, No. 1Psychiatry Research: Neuroimaging, Vol. 91, No. 2Current Opinion in Psychiatry, Vol. 12, No. 4The American Journal of Geriatric Psychiatry, Vol. 7, No. 4British Journal of Psychiatry, Vol. 175, No. 3Outcomes Focused Service Delivery: Developing an Academic-Management Partnership26 June 2016 | Australian & New Zealand Journal of Psychiatry, Vol. 32, No. 3Neuroanatomic Localization of Magnetic Resonance Imaging Signal Hyperintensities in Geriatric DepressionStroke, Vol. 29, No. 3Depression and the Course of Coronary Artery DiseaseAlexander H. Glassman, M.D., and Peter A. Shapiro, M.D.1 January 1998 | American Journal of Psychiatry, Vol. 155, No. 1, Vol. 49Biological Psychiatry, Vol. 43, No. 10American Journal of Geriatric Psychiatry, Vol. 6, No. 3Journal of the American Academy of Nurse Practitioners, Vol. 10, No. 11Journal of Affective Disorders, Vol. 46, No. 3Schizophrenia Research, Vol. 27, No. 2-3Current Opinion in Psychiatry, Vol. 10, No. 2 Volume 153Issue 10 October 1996Pages 1280-1287 Metrics PDF download History Published online 1 April 2006 Published in print 1 October 1996" @default.
• W123841818 created "2016-06-24" @default.
• W123841818 date "1996-10-01" @default.
• W123841818 modified "2023-09-29" @default.
• W123841818 title "Cognition and white matter hyperintensities in older depressed patients" @default.
• W123841818 cites W144734289 @default.
• W123841818 cites W172253351 @default.
• W123841818 cites W172304280 @default.
• W123841818 cites W1817736623 @default.
• W123841818 cites W1847168837 @default.
• W123841818 cites W1964971529 @default.
• W123841818 cites W1974269985 @default.
• W123841818 cites W1978235802 @default.
• W123841818 cites W1980676990 @default.
• W123841818 cites W1983727455 @default.
• W123841818 cites W1989798477 @default.
• W123841818 cites W1994055689 @default.
• W123841818 cites W1999223536 @default.
• W123841818 cites W2010579933 @default.
• W123841818 cites W2010958997 @default.
• W123841818 cites W2014019478 @default.
• W123841818 cites W2014665665 @default.
• W123841818 cites W2019384836 @default.
• W123841818 cites W2023420093 @default.
• W123841818 cites W2026065945 @default.
• W123841818 cites W2026781040 @default.
• W123841818 cites W2035033080 @default.
• W123841818 cites W2038089075 @default.
• W123841818 cites W2039725814 @default.
• W123841818 cites W2041787096 @default.
• W123841818 cites W2045978603 @default.
• W123841818 cites W2047641698 @default.
• W123841818 cites W2057183015 @default.
• W123841818 cites W2061378977 @default.
• W123841818 cites W2065803599 @default.
• W123841818 cites W2066096066 @default.
• W123841818 cites W2074009463 @default.
• W123841818 cites W2074644490 @default.
• W123841818 cites W2075118788 @default.
• W123841818 cites W2076450147 @default.
• W123841818 cites W2081018804 @default.
• W123841818 cites W2090568243 @default.
• W123841818 cites W2091432220 @default.
• W123841818 cites W2093014183 @default.
• W123841818 cites W2094028029 @default.
• W123841818 cites W2114092300 @default.
• W123841818 cites W2132629143 @default.
• W123841818 cites W2154983304 @default.
• W123841818 cites W2158090607 @default.
• W123841818 cites W2160183126 @default.
• W123841818 cites W2166479055 @default.
• W123841818 cites W2169787112 @default.
• W123841818 cites W2411477555 @default.
• W123841818 cites W2413354444 @default.
• W123841818 cites W66853117 @default.
• W123841818 cites W83078694 @default.
• W123841818 doi "https://doi.org/10.1176/ajp.153.10.1280" @default.
• W123841818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8831435" @default.
• W123841818 hasPublicationYear "1996" @default.
• W123841818 type Work @default.
• W123841818 sameAs 123841818 @default.
• W123841818 citedByCount "260" @default.
• W123841818 countsByYear W1238418182012 @default.
• W123841818 countsByYear W1238418182013 @default.
• W123841818 countsByYear W1238418182014 @default.
• W123841818 countsByYear W1238418182015 @default.
• W123841818 countsByYear W1238418182016 @default.
• W123841818 countsByYear W1238418182017 @default.
• W123841818 countsByYear W1238418182018 @default.
• W123841818 countsByYear W1238418182019 @default.
• W123841818 countsByYear W1238418182020 @default.
• W123841818 countsByYear W1238418182021 @default.
• W123841818 countsByYear W1238418182022 @default.
• W123841818 countsByYear W1238418182023 @default.
• W123841818 crossrefType "journal-article" @default.
• W123841818 hasConcept C118552586 @default.
• W123841818 hasConcept C126838900 @default.
• W123841818 hasConcept C143409427 @default.
• W123841818 hasConcept C146638467 @default.
• W123841818 hasConcept C15744967 @default.
• W123841818 hasConcept C169900460 @default.
• W123841818 hasConcept C2781192897 @default.
• W123841818 hasConcept C70410870 @default.
• W123841818 hasConcept C71924100 @default.
• W123841818 hasConcept C74909509 @default.
• W123841818 hasConceptScore W123841818C118552586 @default.
• W123841818 hasConceptScore W123841818C126838900 @default.
• W123841818 hasConceptScore W123841818C143409427 @default.
• W123841818 hasConceptScore W123841818C146638467 @default.
• W123841818 hasConceptScore W123841818C15744967 @default.
• W123841818 hasConceptScore W123841818C169900460 @default.
• W123841818 hasConceptScore W123841818C2781192897 @default.
• W123841818 hasConceptScore W123841818C70410870 @default.
• W123841818 hasConceptScore W123841818C71924100 @default.
• W123841818 hasConceptScore W123841818C74909509 @default.
• W123841818 hasIssue "10" @default.
• W123841818 hasLocation W1238418181 @default.
• W123841818 hasLocation W1238418182 @default.

• next