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- W1239901154 endingPage "275" @default.
- W1239901154 startingPage "257" @default.
- W1239901154 abstract "Chemokines induce rapid hematopoietic stem and progenitor cell mobilization and synergize with hematopoietic cytokines in mobilizing stem and progenitor cells. These proteins alone and in combination offer new paradigms for autologous and allogeneic peripheral blood stem cell transplantation (PBSCT). The mechanisms responsible for hematopoietic stem cell (HSC) mobilization either with growth factors or chemokines are largely unknown, but a better understanding of these mechanisms will permit the development of novel, more rapid and efficacious regimens. Studies presented herein indicate that the CXCR2 chemokine receptor that interacts with selective chemokine ligands, particularly GROβ/CXCL2 and GROβ-T, may be the dominant receptor mediating hematopoietic cell mobilization, and that polymorphonuclear neutrophils may be the primary CXCR2 expressing target cell for stem and progenitor cell mobilization." @default.
- W1239901154 created "2016-06-24" @default.
- W1239901154 creator A5000560911 @default.
- W1239901154 creator A5016341977 @default.
- W1239901154 creator A5059605638 @default.
- W1239901154 creator A5088610750 @default.
- W1239901154 date "2002-09-01" @default.
- W1239901154 modified "2023-10-17" @default.
- W1239901154 title "Peripheral blood stem cell mobilization" @default.
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