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- W124362004 abstract "The questions which led to the present work are also those that led to the discovery of carbonic anhydrase, and thus set in motion the events which led to this conference. It was 50 years ago that the Danish physiologist and physician, Henriques, showed that the uncatalyzed conversion of HCO 3 − to CO2 could not occur rapidly enough to account for the elimination of CO2 in the one second that blood traversed the lungs. He showed that in the presence of blood, however, this reaction was extremely rapid; he speculated that this was due either to a catalytic process or a direct combination of CO2 with hemoglobin. Because it seemed to him that the reaction did not conform to the pattern of an enzymic rate (it was so rapid that he missed readings in the first 5 s) he thought that the carbamino-hemoglobin process was the more likely [4, 5]." @default.
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- W124362004 date "1980-01-01" @default.
- W124362004 modified "2023-09-24" @default.
- W124362004 title "Physiological Consequences of Carbonic Anhydrase Inhibition During Rest and Exercise, and on the Bohr Effect" @default.
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- W124362004 doi "https://doi.org/10.1007/978-3-642-67572-0_42" @default.
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