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- W124662612 abstract "Publisher Summary This chapter presents sheep as an experimental model for immunology in discussing the immunological techniques both in vitro and in vivo. Surgical procedures that insert vinyl and plastic cannula into the afferent and efferent lymphatic ducts of lymph nodes and the intestinal and thoracic lymphatic ducts have enabled the study of cell kinetics in the immune response to percutaneous or intralymphatic infusions of immunogens and in the responses to grafted tissues and organs. By the use of such techniques, the kinetics of entry of blood-borne lymphocytes into lymphoid and other tissues may be monitored, and the cellular and humoral products of immune reactions taking place within lymphoid tissues may be quantitatively and qualitatively assessed in the efferent lymph issuing from the lymph node. In this way, an immune response induced by the infusion of antigen via an afferent lymphatic vessel can be confined to a single lymph node provided the efferent lymphatic vessel has been cannulated and exteriorized." @default.
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- W124662612 date "1985-01-01" @default.
- W124662612 modified "2023-10-07" @default.
- W124662612 title "Sheep as an Experimental Model for Immunology: Immunological Techniques in Vitro and in Vivo" @default.
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- W124662612 doi "https://doi.org/10.1016/b978-0-12-442703-7.50030-9" @default.
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