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• W1247179837 abstract "No AccessJournal of Urology1 Mar 1992Randomized Double Blind Study Comparing the Effectiveness of Balloon Dilation of the Prostate and Cystoscopy for the Treatment of Symptomatic Benign Prostatic Hyperplasia Herbert Lepor, Dirk Sypherd, Grace Machi, and Jeffrey Derus Herbert LeporHerbert Lepor More articles by this author , Dirk SypherdDirk Sypherd More articles by this author , Grace MachiGrace Machi More articles by this author , and Jeffrey DerusJeffrey Derus More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)37331-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We attempted to determine the effectiveness of balloon dilation of the prostate for the treatment of symptomatic benign prostatic hyperplasia (BPH). A total of 33 men with symptomatic BPH signed informed consent to participate in a randomized, double-blind study comparing balloon dilation of the prostate and cystoscopy. Balloon dilation of the prostate and cystoscopy were performed with the patient under intravenous sedation after intraurethral instillation of viscous lidocaine and infiltration of the autonomic neural innervation of the prostate with 1% lidocaine. Efficacy was based upon improvement in Boyarsky symptom scores, increases in peak urinary flow rates and patient global assessment of symptomatic improvement. Efficacy was assessed at 1 and 3 months after treatment. A study nurse blinded to the randomization scheme administered the symptom score questionnaires and supervised the uroflowmetry studies. The study was randomized, since the mean baseline prostate sizes, peak urine flow rates, obstructive and irritative symptom scores, post-void residual volumes and patient ages were similar in the 2 groups. The patient perceptions of treatment rendered were similar for the 2 treatment groups, confirming that the study was double-blind. The patients undergoing cystoscopy and balloon dilation of the prostate experienced a statistically significant improvement in the mean total symptom scores at 1 and 3 months. The mean total symptom scores after balloon dilation of the prostate and cystoscopy at 1 and 3 months were not significantly different. The mean peak urinary flow rates 1 and 3 months after balloon dilation of the prostate and cystoscopy were not significantly different from the baseline mean peak urinary flow rates. We demonstrate that balloon dilation of the prostate and cystoscopy are equally effective for the treatment of BPH. Since cystoscopy is considered a diagnostic modality, our study suggests that the efficacy previously observed after balloon dilation of the prostate is primarily placebo-related. The study does not support the indication of balloon dilation of the prostate for the treatment of symptomatic BPH. © 1992 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByWelliver C, Kottwitz M, Feustel P and McVary K (2018) Clinically and Statistically Significant Changes Seen in Sham Surgery Arms of Randomized, Controlled Benign Prostatic Hyperplasia Surgery TrialsJournal of Urology, VOL. 194, NO. 6, (1682-1687), Online publication date: 1-Dec-2015.McVary K, Roehrborn C, Chartier-Kastler E, Efros M, Bugarin D, Chen R, Patel A and Haag-Molkenteller C (2018) A Multicenter, Randomized, Double-Blind, Placebo Controlled Study of OnabotulinumtoxinA 200 U to Treat Lower Urinary Tract Symptoms in Men With Benign Prostatic HyperplasiaJournal of Urology, VOL. 192, NO. 1, (150-156), Online publication date: 1-Jul-2014. (2018) AUA Guideline on Management of Benign Prostatic Hyperplasia (2003). Chapter 1: Diagnosis and Treatment RecommendationsJournal of Urology, VOL. 170, NO. 2, (530-547), Online publication date: 1-Aug-2003.MUSCHTER R, SCHORSCH I, DANIELLI L, RUSSEL C, TIMONEY A, YACHIA D, JOLKOWSKY E, MATALON G, RODER T and NORDLING J (2018) TRANSURETHRAL WATER-INDUCED THERMOTHERAPY FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA: A PROSPECTIVE MULTICENTER CLINICAL TRIALJournal of Urology, VOL. 164, NO. 5, (1565-1569), Online publication date: 1-Nov-2000.Kaplan S, Laor E, Fatal M and Te A (2018) TRANSURETHRAL RESECTION OF THE PROSTATE VERSUS TRANSURETHRAL ELECTROVAPORIZATION OF THE PROSTATE: A BLINDED, PROSPECTIVE COMPARATIVE STUDY WITH 1-YEAR FOLLOWUPJournal of Urology, VOL. 159, NO. 2, (454-458), Online publication date: 1-Feb-1998.De la Rosette J, D'ancona F and Debruyne F (2018) Current Status of Thermotherapy of the ProstateJournal of Urology, VOL. 157, NO. 2, (430-438), Online publication date: 1-Feb-1997.Tomera K (2018) Re: Transurethral Needle Ablation of the ProstateJournal of Urology, VOL. 157, NO. 3, (964-964), Online publication date: 1-Mar-1997.te Slaa E, Mooibroek J, de Reijke T, Karthaus H, van Capelle J, Tjon Pian Gi N and de la Rosette J (2018) Laser Treatment of the Prostate Using the Urolase Fiber: The Dutch ExperienceJournal of Urology, VOL. 156, NO. 2, (420-425), Online publication date: 1-Aug-1996.Cummings J, Parra R, Boullier J, Crawford K, Petrofsky J and Caulfield J (2018) Evaluation of Fluid Absorption During Laser Prostatectomy by Breath Ethanol TechniquesJournal of Urology, VOL. 154, NO. 6, (2080-2082), Online publication date: 1-Dec-1995.Kaplan S and Te A (2018) A Comparative Study of Transurethral Resection of the Prostate Using a Modified Electro-Vaporizing Loop and Transurethral Laser Vaporization of the ProstateJournal of Urology, VOL. 154, NO. 5, (1785-1790), Online publication date: 1-Nov-1995.Bihrle R, Foster R, Sanghvi N, Donohue J and Hood P (2018) High Intensity Focused Ultrasound for the Treatment of Benign Prostatic Hyperplasia: Early United States Clinical ExperienceJournal of Urology, VOL. 151, NO. 5, (1271-1275), Online publication date: 1-May-1994.Kaplan S and Olsson C (2018) State of the Art: Microwave Therapy in the Management of Men with Benign Prostatic Hyperplasia: Current StatusJournal of Urology, VOL. 150, NO. 5 Part 2, (1597-1602), Online publication date: 1-Nov-1993. Volume 147Issue 3 Part 1March 1992Page: 639-642 Advertisement Copyright & Permissions© 1992 by The American Urological Association Education and Research, Inc.Keywordsballoon dilatationprostatic hypertrophycystoscopyMetricsAuthor Information Herbert Lepor More articles by this author Dirk Sypherd More articles by this author Grace Machi More articles by this author Jeffrey Derus More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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• W1247179837 title "Randomized Double Blind Study Comparing the Effectiveness of Balloon Dilation of the Prostate and Cystoscopy for the Treatment of Symptomatic Benign Prostatic Hyperplasia" @default.
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