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- W1251748139 abstract "BackgroundAutophagy is implicated in Crohn's disease (CD) pathogenesis. Recent evidence suggests autophagy regulates the microRNA (miRNA)-induced silencing complex (miRISC). Therefore, autophagy may play a novel role in CD by regulating expression of miRISC, thereby altering miRNA silencing. As microbes associated with CD can alter autophagy, we hypothesized that microbial disruption of autophagy affects the critical miRISC component AGO2." @default.
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- W1251748139 date "2015-12-01" @default.
- W1251748139 modified "2023-10-10" @default.
- W1251748139 title "Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway" @default.
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- W1251748139 doi "https://doi.org/10.1097/mib.0000000000000553" @default.
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