FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1253550149> ?p ?o ?g. }

• W1253550149 endingPage "395" @default.
• W1253550149 startingPage "383" @default.
• W1253550149 abstract "During human pregnancy, CMV infects the uterine-placental interface with varied outcomes from fetal intrauterine growth restriction to permanent birth defects, depending on the level of maternal immunity and gestational age. Virus spreads from infected uterine blood vessels, amplifies by replicating in decidual cells, and disseminates to the placenta in immune complexes. Cytotrophoblasts--epithelial cells of the placenta--differentiate along two distinct pathways. In the first, cells fuse into syncytiotrophoblasts covering the surface of chorionic villi that transport substances from the maternal to fetal bloodstream. In the second, cells invade the uterine interstitium and blood vessels, remodel the vasculature and form anchoring villi. CMV initiates replication in cytotrophoblast progenitor cells of floating villi, whereas syncytiotrophoblasts are spared. This extraordinary pattern of focal infection in underlying cells hinges on virion receptors being upregulated as villous cytotrophoblasts begin to differentiate. Expression of developmentally regulated receptors could explain viral replication in spatially distinct maternal and fetal compartments. Reduced invasiveness of infected cells could impair remodeling of the uterine vasculature, restrict maternal blood flow and access of the fetus to nutrients causing intrauterine growth restriction." @default.
• W1253550149 created "2016-06-24" @default.
• W1253550149 creator A5021361212 @default.
• W1253550149 creator A5089884694 @default.
• W1253550149 date "2008-01-01" @default.
• W1253550149 modified "2023-10-01" @default.
• W1253550149 title "Cytomegalovirus Infection in the Human Placenta: Maternal Immunity and Developmentally Regulated Receptors on Trophoblasts Converge" @default.
• W1253550149 cites W1558885122 @default.
• W1253550149 cites W1844492615 @default.
• W1253550149 cites W1965181820 @default.
• W1253550149 cites W1974527643 @default.
• W1253550149 cites W1977405208 @default.
• W1253550149 cites W1977494454 @default.
• W1253550149 cites W1980405204 @default.
• W1253550149 cites W1984488701 @default.
• W1253550149 cites W1985955189 @default.
• W1253550149 cites W1986652140 @default.
• W1253550149 cites W1993866784 @default.
• W1253550149 cites W1996688582 @default.
• W1253550149 cites W1997878624 @default.
• W1253550149 cites W1999090873 @default.
• W1253550149 cites W1999913991 @default.
• W1253550149 cites W2005017965 @default.
• W1253550149 cites W2005669726 @default.
• W1253550149 cites W2013150268 @default.
• W1253550149 cites W2022010868 @default.
• W1253550149 cites W2027813788 @default.
• W1253550149 cites W2037351497 @default.
• W1253550149 cites W2037873390 @default.
• W1253550149 cites W2057677145 @default.
• W1253550149 cites W2066695500 @default.
• W1253550149 cites W2068665787 @default.
• W1253550149 cites W2092665836 @default.
• W1253550149 cites W2096792415 @default.
• W1253550149 cites W2103824932 @default.
• W1253550149 cites W2104124112 @default.
• W1253550149 cites W2107506276 @default.
• W1253550149 cites W2109132351 @default.
• W1253550149 cites W2109611320 @default.
• W1253550149 cites W2117834939 @default.
• W1253550149 cites W2128453295 @default.
• W1253550149 cites W2133211985 @default.
• W1253550149 cites W2138771248 @default.
• W1253550149 cites W2142773983 @default.
• W1253550149 cites W2145809469 @default.
• W1253550149 cites W2146075145 @default.
• W1253550149 cites W2149064406 @default.
• W1253550149 cites W2150306998 @default.
• W1253550149 cites W2152588198 @default.
• W1253550149 cites W2155925117 @default.
• W1253550149 cites W2165012523 @default.
• W1253550149 cites W2169069793 @default.
• W1253550149 cites W2616662114 @default.
• W1253550149 cites W287220461 @default.
• W1253550149 cites W4249379626 @default.
• W1253550149 cites W4687941 @default.
• W1253550149 doi "https://doi.org/10.1007/978-3-540-77349-8_21" @default.
• W1253550149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18637517" @default.
• W1253550149 hasPublicationYear "2008" @default.
• W1253550149 type Work @default.
• W1253550149 sameAs 1253550149 @default.
• W1253550149 citedByCount "38" @default.
• W1253550149 countsByYear W12535501492012 @default.
• W1253550149 countsByYear W12535501492013 @default.
• W1253550149 countsByYear W12535501492014 @default.
• W1253550149 countsByYear W12535501492015 @default.
• W1253550149 countsByYear W12535501492016 @default.
• W1253550149 countsByYear W12535501492017 @default.
• W1253550149 countsByYear W12535501492018 @default.
• W1253550149 countsByYear W12535501492019 @default.
• W1253550149 countsByYear W12535501492020 @default.
• W1253550149 countsByYear W12535501492021 @default.
• W1253550149 countsByYear W12535501492022 @default.
• W1253550149 countsByYear W12535501492023 @default.
• W1253550149 crossrefType "book-chapter" @default.
• W1253550149 hasAuthorship W1253550149A5021361212 @default.
• W1253550149 hasAuthorship W1253550149A5089884694 @default.
• W1253550149 hasConcept C170493617 @default.
• W1253550149 hasConcept C172680121 @default.
• W1253550149 hasConcept C203014093 @default.
• W1253550149 hasConcept C2776953305 @default.
• W1253550149 hasConcept C2777495146 @default.
• W1253550149 hasConcept C2777605040 @default.
• W1253550149 hasConcept C2779234561 @default.
• W1253550149 hasConcept C2781385326 @default.
• W1253550149 hasConcept C2908795334 @default.
• W1253550149 hasConcept C45167389 @default.
• W1253550149 hasConcept C54355233 @default.
• W1253550149 hasConcept C55493867 @default.
• W1253550149 hasConcept C86803240 @default.
• W1253550149 hasConcept C95444343 @default.
• W1253550149 hasConceptScore W1253550149C170493617 @default.
• W1253550149 hasConceptScore W1253550149C172680121 @default.
• W1253550149 hasConceptScore W1253550149C203014093 @default.
• W1253550149 hasConceptScore W1253550149C2776953305 @default.
• W1253550149 hasConceptScore W1253550149C2777495146 @default.
• W1253550149 hasConceptScore W1253550149C2777605040 @default.
• W1253550149 hasConceptScore W1253550149C2779234561 @default.

• next