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- W1254929346 abstract "This chapter presents the mechanochemistry of immobilized enzymes. Immobilized enzymes possess another interesting feature that makes them useful in studying fundamental problems of enzymology. On immobilization, a microobject—that is, a molecule of the enzyme, becomes attached to a macroobject— the support. The support, unlike the enzyme, can be subjected to direct mechanical deformation (stretching, compression), which in principle can induce two kinds of effects: alteration of the conformation of the enzyme molecule and change in the properties of the microenvironment in which the molecules of the enzyme are localized. In other words, external mechanical action applied to the support can change the major parameters of the enzyme process. In the laboratories, researchers are engaged in developing this new mechanochemical approach to the mechanistic problems of (a) enzyme catalysis and (b) functioning of natural mechanochemical enzymic systems." @default.
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- W1254929346 date "1976-01-01" @default.
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- W1254929346 title "[39] Mechanochemistrry of immobilized enzymes: A new approach to studies in fundamental enzymology" @default.
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- W1254929346 doi "https://doi.org/10.1016/s0076-6879(76)44041-7" @default.
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