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- W1255344930 abstract "Purpose We reviewed renal function after pyeloplasty (PP) in cases of prenatally diagnosed ureteropelvic junction obstruction (PDUPJO) to determine the impact of preoperative urinary tract infection (UTI) on the timing of PP. Methods We retrospectively reviewed 81 cases of PDUPJO diagnosed between 1998 and 2013. Incidence of UTI was used to divide 37 kidneys requiring PP (3 bilateral) into U(−): UTI ≤ 1; n = 25, and U(+): UTI ≥ 2; n = 12 to compare age at PP, grade of hydronephrosis (HN) on ultrasonography (US), glomerular filtration rate (GFR) on diethylenetriaminepentacetic acid (DTPA) renography, and uptake on dimercaptosuccinic acid (DMSA) scintigraphy pre/post PP. Results Age at first UTI and age at PP were similar. HN improved significantly postPP in all cases. Although DTPA and DMSA were similar prePP, improvement postPP was better in U(−) than U(+), but only DMSA in U(−) was statistically significant (15.2% ± 4.0% vs. 20% ± 3.7%; p = 0.049). There were no complications or UTI postPP. Conclusion Two or more UTIs would appear to be associated with postPP renal dysfunction in PDUPJO. Thus, PP should be performed after the initial UTI but before the second UTI." @default.
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- W1255344930 date "2015-12-01" @default.
- W1255344930 modified "2023-10-17" @default.
- W1255344930 title "The effect of preoperative urinary tract infection on postoperative renal function in prenatally diagnosed ureteropelvic junction obstruction: Indications for the timing of pyeloplasty" @default.
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- W1255344930 doi "https://doi.org/10.1016/j.jpedsurg.2015.08.030" @default.
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