Matches in SemOpenAlex for { <https://semopenalex.org/work/W125837126> ?p ?o ?g. }
- W125837126 endingPage "191" @default.
- W125837126 startingPage "177" @default.
- W125837126 abstract "There has been tremendous effort aimed at developing adjuvants that promote proinflammatory and/or strong cell-mediated immunity; many are discussed in this book. Interestingly, little effort is being placed on development of adjuvants that promote T helper (Th)2-type antibody responses. In part, this may be because alum has proven to be a safe, well-tolerated adjuvant that does bias the immune response in vaccine recipients toward Th2-type responses (1, 2). Additionally, it may because of the perception that Th2-biased immune responses will not provide protection, or that they will not elicit strong cell-mediated responses to vaccine antigens, which is generally true for viral vaccines. However, there are disease situations in which driving Th2 responses is warranted, in particular for helminth infections, many of which require Th2-type responses for immune elimination of parasites (3–5). The second major category would be for preventive and/or therapeutic vaccines for proinflammatory-based autoimmune diseases. This category of diseases is increasing dramatically in humans and their pets. Clearly the use of adjuvants, which drive Th2-biased and/or anti-inflammatory responses, would be beneficial here. In fact, the tremendous increase in proinflammatory autoimmune diseases suggests that it is prudent to limit exposure to strong proinflammatory driving adjuvants and vaccines that promote Th1-type responses." @default.
- W125837126 created "2016-06-24" @default.
- W125837126 creator A5015425721 @default.
- W125837126 creator A5015751956 @default.
- W125837126 creator A5035851025 @default.
- W125837126 creator A5042328410 @default.
- W125837126 creator A5057646685 @default.
- W125837126 creator A5060017067 @default.
- W125837126 date "2006-01-01" @default.
- W125837126 modified "2023-10-16" @default.
- W125837126 title "The Immunomodulatory Glycan LNFPIII/Lewis X Functions As a Potent Adjuvant for Protein Antigens" @default.
- W125837126 cites W121151937 @default.
- W125837126 cites W1540076991 @default.
- W125837126 cites W1555655466 @default.
- W125837126 cites W1558372199 @default.
- W125837126 cites W1564469788 @default.
- W125837126 cites W1656812865 @default.
- W125837126 cites W1661544713 @default.
- W125837126 cites W1834719122 @default.
- W125837126 cites W1881253097 @default.
- W125837126 cites W1950874980 @default.
- W125837126 cites W1965366343 @default.
- W125837126 cites W1967149617 @default.
- W125837126 cites W1970922508 @default.
- W125837126 cites W1972922050 @default.
- W125837126 cites W1973978881 @default.
- W125837126 cites W1977561461 @default.
- W125837126 cites W1985054040 @default.
- W125837126 cites W1987110980 @default.
- W125837126 cites W1998733027 @default.
- W125837126 cites W2004773897 @default.
- W125837126 cites W2014385809 @default.
- W125837126 cites W2014399113 @default.
- W125837126 cites W2034197799 @default.
- W125837126 cites W2038018517 @default.
- W125837126 cites W2050975259 @default.
- W125837126 cites W2051157744 @default.
- W125837126 cites W2062683793 @default.
- W125837126 cites W2062811432 @default.
- W125837126 cites W2065927080 @default.
- W125837126 cites W2079961392 @default.
- W125837126 cites W2087166273 @default.
- W125837126 cites W2089923520 @default.
- W125837126 cites W2097856417 @default.
- W125837126 cites W2108396734 @default.
- W125837126 cites W2111220263 @default.
- W125837126 cites W2111345507 @default.
- W125837126 cites W2114737175 @default.
- W125837126 cites W2125202093 @default.
- W125837126 cites W2128055100 @default.
- W125837126 cites W2130454747 @default.
- W125837126 cites W2130850730 @default.
- W125837126 cites W2131775087 @default.
- W125837126 cites W2135586660 @default.
- W125837126 cites W2135806909 @default.
- W125837126 cites W2146591550 @default.
- W125837126 cites W2146671478 @default.
- W125837126 cites W2158865185 @default.
- W125837126 cites W2160655212 @default.
- W125837126 cites W2161426250 @default.
- W125837126 cites W2161504113 @default.
- W125837126 cites W2162366282 @default.
- W125837126 cites W2166417236 @default.
- W125837126 cites W2172466148 @default.
- W125837126 cites W2206351253 @default.
- W125837126 cites W53979418 @default.
- W125837126 doi "https://doi.org/10.1007/978-1-59259-970-7_9" @default.
- W125837126 hasPublicationYear "2006" @default.
- W125837126 type Work @default.
- W125837126 sameAs 125837126 @default.
- W125837126 citedByCount "1" @default.
- W125837126 crossrefType "book-chapter" @default.
- W125837126 hasAuthorship W125837126A5015425721 @default.
- W125837126 hasAuthorship W125837126A5015751956 @default.
- W125837126 hasAuthorship W125837126A5035851025 @default.
- W125837126 hasAuthorship W125837126A5042328410 @default.
- W125837126 hasAuthorship W125837126A5057646685 @default.
- W125837126 hasAuthorship W125837126A5060017067 @default.
- W125837126 hasConcept C147483822 @default.
- W125837126 hasConcept C164027704 @default.
- W125837126 hasConcept C203014093 @default.
- W125837126 hasConcept C2776914184 @default.
- W125837126 hasConcept C2777863537 @default.
- W125837126 hasConcept C2779341262 @default.
- W125837126 hasConcept C71924100 @default.
- W125837126 hasConcept C86803240 @default.
- W125837126 hasConcept C8891405 @default.
- W125837126 hasConceptScore W125837126C147483822 @default.
- W125837126 hasConceptScore W125837126C164027704 @default.
- W125837126 hasConceptScore W125837126C203014093 @default.
- W125837126 hasConceptScore W125837126C2776914184 @default.
- W125837126 hasConceptScore W125837126C2777863537 @default.
- W125837126 hasConceptScore W125837126C2779341262 @default.
- W125837126 hasConceptScore W125837126C71924100 @default.
- W125837126 hasConceptScore W125837126C86803240 @default.
- W125837126 hasConceptScore W125837126C8891405 @default.
- W125837126 hasLocation W1258371261 @default.
- W125837126 hasOpenAccess W125837126 @default.