FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1262470259> ?p ?o ?g. }

• W1262470259 endingPage "935" @default.
• W1262470259 startingPage "929" @default.
• W1262470259 abstract "Lactase-phlorizin hydrolase (LPH) is expressed on the intestinal brush border and is responsible for the hydrolysis of lactose, the chief sugar in mammalian milk. The enzyme activity of LPH peaks soon after birth in most mammals and declines to much lower levels before adolescence. The molecular basis of this pattern of expression has not been clearly established. We have measured relative amounts of LPH mRNA in intestine from sheep with ages across a developmental spectrum, including third trimester fetal lambs, newborn lambs and adult sheep. LPH mRNA levels in the jejunum decline approximately 50-fold between infancy and adulthood, in parallel with the reduction in both lactase specific activity and immunologically reactive lactase protein expression in sheep jejunum. LPH mRNA is present in high concentration in the duodenum of newborn lambs, but steadily declines by day 34 and is dramatically reduced in adults. Because the changes in LPH mRNA, protein, and enzymic activity are generally parallel, we conclude that the developmental regulation of LPH in sheep is probably mediated primarily at the mRNA level." @default.
• W1262470259 created "2016-06-24" @default.
• W1262470259 creator A5009029194 @default.
• W1262470259 creator A5014751224 @default.
• W1262470259 creator A5031899628 @default.
• W1262470259 creator A5038739529 @default.
• W1262470259 creator A5044873395 @default.
• W1262470259 date "1994-09-15" @default.
• W1262470259 modified "2023-09-23" @default.
• W1262470259 title "Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level" @default.
• W1262470259 cites W1506033718 @default.
• W1262470259 cites W1514426880 @default.
• W1262470259 cites W151800883 @default.
• W1262470259 cites W1519777513 @default.
• W1262470259 cites W1522309202 @default.
• W1262470259 cites W1560053074 @default.
• W1262470259 cites W1626598639 @default.
• W1262470259 cites W1637460429 @default.
• W1262470259 cites W1798048537 @default.
• W1262470259 cites W1904451644 @default.
• W1262470259 cites W1983912277 @default.
• W1262470259 cites W1989075870 @default.
• W1262470259 cites W2017410870 @default.
• W1262470259 cites W2018289835 @default.
• W1262470259 cites W2027132036 @default.
• W1262470259 cites W2060333964 @default.
• W1262470259 cites W2066719256 @default.
• W1262470259 cites W2077227518 @default.
• W1262470259 cites W2098293146 @default.
• W1262470259 cites W2100837269 @default.
• W1262470259 cites W2107670778 @default.
• W1262470259 cites W2110389243 @default.
• W1262470259 cites W2128635872 @default.
• W1262470259 cites W2138039905 @default.
• W1262470259 cites W2138270253 @default.
• W1262470259 cites W2147544567 @default.
• W1262470259 cites W2153541582 @default.
• W1262470259 cites W25055955 @default.
• W1262470259 cites W7386683 @default.
• W1262470259 cites W88529908 @default.
• W1262470259 doi "https://doi.org/10.1042/bj3020929" @default.
• W1262470259 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1137319" @default.
• W1262470259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7945222" @default.
• W1262470259 hasPublicationYear "1994" @default.
• W1262470259 type Work @default.
• W1262470259 sameAs 1262470259 @default.
• W1262470259 citedByCount "30" @default.
• W1262470259 countsByYear W12624702592013 @default.
• W1262470259 countsByYear W12624702592014 @default.
• W1262470259 countsByYear W12624702592018 @default.
• W1262470259 countsByYear W12624702592021 @default.
• W1262470259 countsByYear W12624702592022 @default.
• W1262470259 crossrefType "journal-article" @default.
• W1262470259 hasAuthorship W1262470259A5009029194 @default.
• W1262470259 hasAuthorship W1262470259A5014751224 @default.
• W1262470259 hasAuthorship W1262470259A5031899628 @default.
• W1262470259 hasAuthorship W1262470259A5038739529 @default.
• W1262470259 hasAuthorship W1262470259A5044873395 @default.
• W1262470259 hasBestOaLocation W12624702592 @default.
• W1262470259 hasConcept C104317684 @default.
• W1262470259 hasConcept C105580179 @default.
• W1262470259 hasConcept C126322002 @default.
• W1262470259 hasConcept C130316041 @default.
• W1262470259 hasConcept C134018914 @default.
• W1262470259 hasConcept C150194340 @default.
• W1262470259 hasConcept C161573976 @default.
• W1262470259 hasConcept C16685009 @default.
• W1262470259 hasConcept C181199279 @default.
• W1262470259 hasConcept C2776366702 @default.
• W1262470259 hasConcept C2776809568 @default.
• W1262470259 hasConcept C2778117581 @default.
• W1262470259 hasConcept C2778724459 @default.
• W1262470259 hasConcept C2778974006 @default.
• W1262470259 hasConcept C2779306644 @default.
• W1262470259 hasConcept C2780120296 @default.
• W1262470259 hasConcept C41625074 @default.
• W1262470259 hasConcept C43053761 @default.
• W1262470259 hasConcept C5426402 @default.
• W1262470259 hasConcept C55493867 @default.
• W1262470259 hasConcept C71924100 @default.
• W1262470259 hasConcept C86803240 @default.
• W1262470259 hasConceptScore W1262470259C104317684 @default.
• W1262470259 hasConceptScore W1262470259C105580179 @default.
• W1262470259 hasConceptScore W1262470259C126322002 @default.
• W1262470259 hasConceptScore W1262470259C130316041 @default.
• W1262470259 hasConceptScore W1262470259C134018914 @default.
• W1262470259 hasConceptScore W1262470259C150194340 @default.
• W1262470259 hasConceptScore W1262470259C161573976 @default.
• W1262470259 hasConceptScore W1262470259C16685009 @default.
• W1262470259 hasConceptScore W1262470259C181199279 @default.
• W1262470259 hasConceptScore W1262470259C2776366702 @default.
• W1262470259 hasConceptScore W1262470259C2776809568 @default.
• W1262470259 hasConceptScore W1262470259C2778117581 @default.
• W1262470259 hasConceptScore W1262470259C2778724459 @default.
• W1262470259 hasConceptScore W1262470259C2778974006 @default.
• W1262470259 hasConceptScore W1262470259C2779306644 @default.
• W1262470259 hasConceptScore W1262470259C2780120296 @default.
• W1262470259 hasConceptScore W1262470259C41625074 @default.

• next