Matches in SemOpenAlex for { <https://semopenalex.org/work/W1270647564> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W1270647564 endingPage "610" @default.
- W1270647564 startingPage "605" @default.
- W1270647564 abstract "Because it is relatively insoluble, the oxidant gas O3 may penetrate to small peripheral airways when it is inhaled. Increased responsiveness in large airways after O3 breathing has been associated with the presence of inflammatory cells. To determine whether O3 produces prolonged hyperresponsiveness of small airways associated with the presence of inflammatory cells, we exposed the peripheral lungs of anesthetized dogs to 1.0 ppm O3 for 2 h using a wedged bronchoscope technique. A contralateral sublobar segment was simultaneously exposed to air as a control. In the O3-exposed segments, collateral resistance (Rcs) was increased within 15 min and remained elevated approximately 150% throughout the 2-h exposure period. Fifteen hours later, the base-line Rcs of the O3-exposed sublobar segments was significantly elevated, and these segments demonstrated increased responsiveness to aerosolized acetylcholine (100 and 500 micrograms/ml). There were no differences in neutrophils, mononuclear cells, or mast cells (numbers or degree of mast cell degranulation) between O3 and air-exposed airways at 15 h. The small airways of the lung periphery thus are capable of remaining hyperresponsive hours after cessation of localized exposure to O3, but this does not appear to be dependent on the presence of inflammatory cells in the small airway wall." @default.
- W1270647564 created "2016-06-24" @default.
- W1270647564 creator A5014009461 @default.
- W1270647564 creator A5021914457 @default.
- W1270647564 creator A5038600501 @default.
- W1270647564 creator A5053257845 @default.
- W1270647564 date "1988-02-01" @default.
- W1270647564 modified "2023-10-16" @default.
- W1270647564 title "Prolonged increased responsiveness of canine peripheral airways after exposure to O3" @default.
- W1270647564 doi "https://doi.org/10.1152/jappl.1988.64.2.605" @default.
- W1270647564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3372418" @default.
- W1270647564 hasPublicationYear "1988" @default.
- W1270647564 type Work @default.
- W1270647564 sameAs 1270647564 @default.
- W1270647564 citedByCount "8" @default.
- W1270647564 countsByYear W12706475642020 @default.
- W1270647564 crossrefType "journal-article" @default.
- W1270647564 hasAuthorship W1270647564A5014009461 @default.
- W1270647564 hasAuthorship W1270647564A5021914457 @default.
- W1270647564 hasAuthorship W1270647564A5038600501 @default.
- W1270647564 hasAuthorship W1270647564A5053257845 @default.
- W1270647564 hasConcept C126322002 @default.
- W1270647564 hasConcept C142724271 @default.
- W1270647564 hasConcept C170493617 @default.
- W1270647564 hasConcept C203014093 @default.
- W1270647564 hasConcept C2776178081 @default.
- W1270647564 hasConcept C2777714996 @default.
- W1270647564 hasConcept C2780314925 @default.
- W1270647564 hasConcept C33362165 @default.
- W1270647564 hasConcept C46762472 @default.
- W1270647564 hasConcept C49802076 @default.
- W1270647564 hasConcept C534529494 @default.
- W1270647564 hasConcept C71924100 @default.
- W1270647564 hasConceptScore W1270647564C126322002 @default.
- W1270647564 hasConceptScore W1270647564C142724271 @default.
- W1270647564 hasConceptScore W1270647564C170493617 @default.
- W1270647564 hasConceptScore W1270647564C203014093 @default.
- W1270647564 hasConceptScore W1270647564C2776178081 @default.
- W1270647564 hasConceptScore W1270647564C2777714996 @default.
- W1270647564 hasConceptScore W1270647564C2780314925 @default.
- W1270647564 hasConceptScore W1270647564C33362165 @default.
- W1270647564 hasConceptScore W1270647564C46762472 @default.
- W1270647564 hasConceptScore W1270647564C49802076 @default.
- W1270647564 hasConceptScore W1270647564C534529494 @default.
- W1270647564 hasConceptScore W1270647564C71924100 @default.
- W1270647564 hasIssue "2" @default.
- W1270647564 hasLocation W12706475641 @default.
- W1270647564 hasLocation W12706475642 @default.
- W1270647564 hasOpenAccess W1270647564 @default.
- W1270647564 hasPrimaryLocation W12706475641 @default.
- W1270647564 hasRelatedWork W1510319286 @default.
- W1270647564 hasRelatedWork W1991288089 @default.
- W1270647564 hasRelatedWork W1995209043 @default.
- W1270647564 hasRelatedWork W2137957356 @default.
- W1270647564 hasRelatedWork W2229090600 @default.
- W1270647564 hasRelatedWork W2261019224 @default.
- W1270647564 hasRelatedWork W2331442940 @default.
- W1270647564 hasRelatedWork W2460194000 @default.
- W1270647564 hasRelatedWork W4229450505 @default.
- W1270647564 hasRelatedWork W6875111 @default.
- W1270647564 hasVolume "64" @default.
- W1270647564 isParatext "false" @default.
- W1270647564 isRetracted "false" @default.
- W1270647564 magId "1270647564" @default.
- W1270647564 workType "article" @default.