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• W1272006043 startingPage "28" @default.
• W1272006043 abstract "Nogo-A is a myelin associated protein and one of the most potent neurite growth inhibitors in the central nervous system. Interference with Nogo-A signaling has thus been investigated as therapeutic target to promote functional recovery in CNS injuries. Still, the finding that Nogo-A presents a fairly ubiquitous expression in many types of neurons in different brain regions, in the eye and even in the inner ear suggests for further functions besides the neurite growth repression. Indeed, a growing number of studies identified a variety of functions including regulation of neuronal stem cells, modulation of microglial activity, inhibition of angiogenesis and interference with memory formation. Aim of the present commentary is to draw attention on these less well-known and sometimes controversial roles of Nogo-A. Furthermore, we are addressing the role of Nogo-A in neuropathological conditions such as ischemic stroke, schizophrenia and neurodegenerative diseases." @default.
• W1272006043 created "2016-06-24" @default.
• W1272006043 creator A5037861132 @default.
• W1272006043 creator A5045691648 @default.
• W1272006043 date "2016-01-01" @default.
• W1272006043 modified "2023-09-26" @default.
• W1272006043 title "Non-canonical actions of Nogo-A and its receptors" @default.
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