Matches in SemOpenAlex for { <https://semopenalex.org/work/W127220693> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W127220693 abstract "The objective of this study was to determine whether variation in energy expenditure created by selection on heat loss is mediated by uncoupling protein-1 (UCP1) in brown adipose tissue. Divergent selection for heat loss developed lines of mice with high (MH) and low (ML) maintenance energy expenditure. Concentration of UCP1 mRNA in brown adipose tissue (BAT) was 93% greater in ML than in MH mice (P < 0.02). Two new lines of mice, KH and KL, were bred by backcrossing a UCP1 knockout gene into the MH and ML lines, respectively; KH and KL with both knock-out (-/-) and wild type (+/+) UCP1 genotypes were generated. At 13 wk of age, KH mice exhibited greater heat loss (166 kcal x kg(0.75) x d(-1)) than KL mice (126.4 kcalkg(0.75) x d(-1)) regardless of the UCP1 knockout (P < 0.0001). Concentration of UCP2 mRNA in BAT was 74% greater in UCP1 knockout mice (-/-) than in wild type (+/+; P = 0.0001). We conclude that response to selection for increased energy expenditure was not mediated by increased expression or function of UCP1." @default.
- W127220693 created "2016-06-24" @default.
- W127220693 creator A5008677085 @default.
- W127220693 creator A5057382988 @default.
- W127220693 creator A5073174993 @default.
- W127220693 date "2002-03-01" @default.
- W127220693 modified "2023-09-27" @default.
- W127220693 title "Uncoupling proteins and energy expenditure in mice divergently selected for heat loss" @default.
- W127220693 doi "https://doi.org/10.2527/2002.803602x" @default.
- W127220693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11890396" @default.
- W127220693 hasPublicationYear "2002" @default.
- W127220693 type Work @default.
- W127220693 sameAs 127220693 @default.
- W127220693 citedByCount "6" @default.
- W127220693 countsByYear W1272206932012 @default.
- W127220693 countsByYear W1272206932013 @default.
- W127220693 countsByYear W1272206932019 @default.
- W127220693 countsByYear W1272206932020 @default.
- W127220693 crossrefType "journal-article" @default.
- W127220693 hasAuthorship W127220693A5008677085 @default.
- W127220693 hasAuthorship W127220693A5057382988 @default.
- W127220693 hasAuthorship W127220693A5073174993 @default.
- W127220693 hasBestOaLocation W1272206932 @default.
- W127220693 hasConcept C104317684 @default.
- W127220693 hasConcept C126322002 @default.
- W127220693 hasConcept C134018914 @default.
- W127220693 hasConcept C143065580 @default.
- W127220693 hasConcept C151279926 @default.
- W127220693 hasConcept C171089720 @default.
- W127220693 hasConcept C182704531 @default.
- W127220693 hasConcept C185592680 @default.
- W127220693 hasConcept C207583985 @default.
- W127220693 hasConcept C2779406938 @default.
- W127220693 hasConcept C2780642333 @default.
- W127220693 hasConcept C2988147884 @default.
- W127220693 hasConcept C55493867 @default.
- W127220693 hasConcept C71924100 @default.
- W127220693 hasConcept C77957584 @default.
- W127220693 hasConcept C81979416 @default.
- W127220693 hasConcept C86803240 @default.
- W127220693 hasConceptScore W127220693C104317684 @default.
- W127220693 hasConceptScore W127220693C126322002 @default.
- W127220693 hasConceptScore W127220693C134018914 @default.
- W127220693 hasConceptScore W127220693C143065580 @default.
- W127220693 hasConceptScore W127220693C151279926 @default.
- W127220693 hasConceptScore W127220693C171089720 @default.
- W127220693 hasConceptScore W127220693C182704531 @default.
- W127220693 hasConceptScore W127220693C185592680 @default.
- W127220693 hasConceptScore W127220693C207583985 @default.
- W127220693 hasConceptScore W127220693C2779406938 @default.
- W127220693 hasConceptScore W127220693C2780642333 @default.
- W127220693 hasConceptScore W127220693C2988147884 @default.
- W127220693 hasConceptScore W127220693C55493867 @default.
- W127220693 hasConceptScore W127220693C71924100 @default.
- W127220693 hasConceptScore W127220693C77957584 @default.
- W127220693 hasConceptScore W127220693C81979416 @default.
- W127220693 hasConceptScore W127220693C86803240 @default.
- W127220693 hasLocation W1272206931 @default.
- W127220693 hasLocation W1272206932 @default.
- W127220693 hasLocation W1272206933 @default.
- W127220693 hasOpenAccess W127220693 @default.
- W127220693 hasPrimaryLocation W1272206931 @default.
- W127220693 hasRelatedWork W1554746149 @default.
- W127220693 hasRelatedWork W1966910952 @default.
- W127220693 hasRelatedWork W1977728293 @default.
- W127220693 hasRelatedWork W1982682208 @default.
- W127220693 hasRelatedWork W1996686320 @default.
- W127220693 hasRelatedWork W2031944235 @default.
- W127220693 hasRelatedWork W2039385620 @default.
- W127220693 hasRelatedWork W2055297296 @default.
- W127220693 hasRelatedWork W2061554116 @default.
- W127220693 hasRelatedWork W2062073832 @default.
- W127220693 hasRelatedWork W2076784345 @default.
- W127220693 hasRelatedWork W2077388284 @default.
- W127220693 hasRelatedWork W2088459933 @default.
- W127220693 hasRelatedWork W2107552685 @default.
- W127220693 hasRelatedWork W2140792176 @default.
- W127220693 hasRelatedWork W2175806519 @default.
- W127220693 hasRelatedWork W2185793661 @default.
- W127220693 hasRelatedWork W2202074724 @default.
- W127220693 hasRelatedWork W2276621227 @default.
- W127220693 hasRelatedWork W2332108806 @default.
- W127220693 isParatext "false" @default.
- W127220693 isRetracted "false" @default.
- W127220693 magId "127220693" @default.
- W127220693 workType "article" @default.