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- W127518936 abstract "Abstract Increased production has been the major goal of animal breeding for many decades, and the correlated side-effects have grown to become a major issue in animal welfare. In this paper, the main genetic mechanisms in which such side-effects may occur are reviewed with examples from our own research in chickens. Pleiotropy, linkage and regulatory pathways are the most important means by which a number of traits may be affected simultaneously by the same selection pressure. Pleiotropy can be exemplified by the gene PMEL17 which causes a lack of black pigmentation in chickens and, simultaneously, predisposes them to become the victims of feather pecking. Linkage is a probable reason why a limited region on chicken chromosome 1 affects many different traits, such as growth, reproduction and fear-related behaviour. Gene regulation is affected by stress, and may cause modifications in behaviour and phenotype which are transferred from parents to offspring by means of epigenetic modifications. Insights into phenomena, such as these, may increase our understanding not only of how artificial selection works, but also evolution at large." @default.
- W127518936 created "2016-06-24" @default.
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- W127518936 date "2010-05-01" @default.
- W127518936 modified "2023-10-11" @default.
- W127518936 title "Domestication, selection, behaviour and welfare of animals — genetic mechanisms for rapid responses" @default.
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- W127518936 doi "https://doi.org/10.1017/s0962728600002189" @default.
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