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• W127673679 abstract "The domestic cat, currently the most frequent of companion animals, has enjoyed a medical surveillance, as a nonprimate species, second only to the dog. With over 200 hereditary disease pathologies reported in the cat, the clinical and physiological study of these feline hereditary diseases provides a strong comparative medicine opportunity for prevention, diagnostics, and treatment studies in a laboratory setting. Causal mutations have been characterized in 19 felid genes, with the largest representation from lysosomal storage enzyme disorders. Corrective therapeutic strategies for several disorders have been proposed and examined in the cat, including enzyme replacement, heterologous bone marrow transplantation, and substrate reduction therapy. Genomics tools developed in the cat, including the recent completion of the 2-fold whole genome sequence of the cat and genome browser, radiation hybrid map of 1793 integrated coding and microsatellite loci, a 5-cM genetic linkage map, arrayed BAC libraries, and flow sorted chromosomes, are providing resources that are being utilized in mapping and characterization of genes of interest. A recent report of the mapping and characterization of a novel causative gene for feline spinal muscular atrophy marked the first identification of a disease gene purely from positional reasoning. With the development of genomic resources in the cat and the application of complementary comparative tools developed in other species, the domestic cat is emerging as a promising resource of phenotypically defined genetic variation of biomedical significance. Additionally, the cat has provided several useful models for infectious disease. These include feline leukemia and feline sarcoma virus, feline coronavirus, and Type C retroviruses that interact with cellular oncogenes to induce leukemia, lymphoma, and sarcoma." @default.
• W127673679 created "2016-06-24" @default.
• W127673679 creator A5027601427 @default.
• W127673679 creator A5063971899 @default.
• W127673679 date "2008-01-01" @default.
• W127673679 modified "2023-10-14" @default.
• W127673679 title "The Domestic Cat, Felis catus, as a Model of Hereditary and Infectious Disease" @default.
• W127673679 cites W1482359363 @default.
• W127673679 cites W1621273311 @default.
• W127673679 cites W1760054562 @default.
• W127673679 cites W1934816453 @default.
• W127673679 cites W1963496509 @default.
• W127673679 cites W1963559963 @default.
• W127673679 cites W1967258269 @default.
• W127673679 cites W1967800726 @default.
• W127673679 cites W1969429424 @default.
• W127673679 cites W1969997927 @default.
• W127673679 cites W1973701820 @default.
• W127673679 cites W1975949502 @default.
• W127673679 cites W1980477780 @default.
• W127673679 cites W1980868415 @default.
• W127673679 cites W1981070147 @default.
• W127673679 cites W1981870321 @default.
• W127673679 cites W1982162156 @default.
• W127673679 cites W1984433501 @default.
• W127673679 cites W1984774545 @default.
• W127673679 cites W1985420747 @default.
• W127673679 cites W1988589573 @default.
• W127673679 cites W1990903685 @default.
• W127673679 cites W1991195026 @default.
• W127673679 cites W1993205220 @default.
• W127673679 cites W1997014864 @default.
• W127673679 cites W2009208457 @default.
• W127673679 cites W2011537206 @default.
• W127673679 cites W2012261031 @default.
• W127673679 cites W2012817490 @default.
• W127673679 cites W2013831089 @default.
• W127673679 cites W2015944007 @default.
• W127673679 cites W2018139041 @default.
• W127673679 cites W2018168676 @default.
• W127673679 cites W2020620545 @default.
• W127673679 cites W2025763389 @default.
• W127673679 cites W2027210778 @default.
• W127673679 cites W2027989840 @default.
• W127673679 cites W2028113696 @default.
• W127673679 cites W2028831791 @default.
• W127673679 cites W2028861758 @default.
• W127673679 cites W2029293367 @default.
• W127673679 cites W2029542216 @default.
• W127673679 cites W2030150604 @default.
• W127673679 cites W2031355940 @default.
• W127673679 cites W2032008131 @default.
• W127673679 cites W2032605897 @default.
• W127673679 cites W2037173572 @default.
• W127673679 cites W2042546823 @default.
• W127673679 cites W2042955700 @default.
• W127673679 cites W2044616650 @default.
• W127673679 cites W2045396403 @default.
• W127673679 cites W2045403748 @default.
• W127673679 cites W2055467457 @default.
• W127673679 cites W2056351306 @default.
• W127673679 cites W2060311755 @default.
• W127673679 cites W2062411083 @default.
• W127673679 cites W2066180106 @default.
• W127673679 cites W2069061113 @default.
• W127673679 cites W2071169720 @default.
• W127673679 cites W2071671321 @default.
• W127673679 cites W2072458000 @default.
• W127673679 cites W2074469168 @default.
• W127673679 cites W2074609350 @default.
• W127673679 cites W2076828557 @default.
• W127673679 cites W2077064092 @default.
• W127673679 cites W2082262146 @default.
• W127673679 cites W2085728331 @default.
• W127673679 cites W2086585629 @default.
• W127673679 cites W2087530582 @default.
• W127673679 cites W2088789807 @default.
• W127673679 cites W2091354486 @default.
• W127673679 cites W2093377166 @default.
• W127673679 cites W2094598342 @default.
• W127673679 cites W2096630266 @default.
• W127673679 cites W2098001104 @default.
• W127673679 cites W2099339386 @default.
• W127673679 cites W2100382193 @default.
• W127673679 cites W2101489471 @default.
• W127673679 cites W2101970065 @default.
• W127673679 cites W2102159052 @default.
• W127673679 cites W2102555948 @default.
• W127673679 cites W2105415356 @default.
• W127673679 cites W2106823728 @default.
• W127673679 cites W2109553414 @default.
• W127673679 cites W2111919213 @default.
• W127673679 cites W2114611642 @default.
• W127673679 cites W2116586125 @default.
• W127673679 cites W2118066208 @default.
• W127673679 cites W2118973459 @default.
• W127673679 cites W2120113718 @default.
• W127673679 cites W2122709595 @default.

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