Matches in SemOpenAlex for { <https://semopenalex.org/work/W127962669> ?p ?o ?g. }
- W127962669 abstract "In this chapter we review the different technologies that can be applied in the analysis of protein homeostasis and metabolism in aging research. Special focus will be on technologies with a potential to circumvent the problems associated with cell heterogeneity in biomarker discovery. Often studies aimed at increasing our understanding of cellular senescence take advantage of model systems. This can be in the form of cell culture, where specific celllines are cultivated, thus undergoing cellular senescence according to the Hayflick phenomenon. Alternatively, model organisms can be included, such as yeast, nematodes and zebra fish. Even though such model systems allow the researcher to control many parameters of the system, it is well established that even in a simple cell culture system the individual cells are morphologically and functionally different. The heterogeneity observed even within the least complex systems, makes it a difficult task to identify biomarkers of cellular senescence and to fully understand the various molecular networks. The complexity is further increased when taking the step from model systems of aging to human aging." @default.
- W127962669 created "2016-06-24" @default.
- W127962669 creator A5002597093 @default.
- W127962669 creator A5006943587 @default.
- W127962669 date "2010-01-01" @default.
- W127962669 modified "2023-09-27" @default.
- W127962669 title "Confronting Cellular Heterogeneity in Studies of Protein Metabolism and Homeostasis in Aging Research" @default.
- W127962669 cites W1485730287 @default.
- W127962669 cites W1966328487 @default.
- W127962669 cites W1968893466 @default.
- W127962669 cites W1970924670 @default.
- W127962669 cites W1983233303 @default.
- W127962669 cites W1983678429 @default.
- W127962669 cites W1987113650 @default.
- W127962669 cites W1987896052 @default.
- W127962669 cites W1988643611 @default.
- W127962669 cites W1988894839 @default.
- W127962669 cites W1992933422 @default.
- W127962669 cites W1993575340 @default.
- W127962669 cites W1996291620 @default.
- W127962669 cites W1996796847 @default.
- W127962669 cites W1998162097 @default.
- W127962669 cites W1998910499 @default.
- W127962669 cites W2001263173 @default.
- W127962669 cites W2004103759 @default.
- W127962669 cites W2004205775 @default.
- W127962669 cites W2004314923 @default.
- W127962669 cites W2006208739 @default.
- W127962669 cites W2008580617 @default.
- W127962669 cites W2011261569 @default.
- W127962669 cites W2014428796 @default.
- W127962669 cites W2016789574 @default.
- W127962669 cites W2020038931 @default.
- W127962669 cites W2023655799 @default.
- W127962669 cites W2024288744 @default.
- W127962669 cites W2026629877 @default.
- W127962669 cites W2031154947 @default.
- W127962669 cites W2033657859 @default.
- W127962669 cites W2039175545 @default.
- W127962669 cites W2041096011 @default.
- W127962669 cites W2043367798 @default.
- W127962669 cites W2048333869 @default.
- W127962669 cites W2050853391 @default.
- W127962669 cites W2054218003 @default.
- W127962669 cites W2055214702 @default.
- W127962669 cites W2060101911 @default.
- W127962669 cites W2061530347 @default.
- W127962669 cites W2066239138 @default.
- W127962669 cites W2066857567 @default.
- W127962669 cites W2069529584 @default.
- W127962669 cites W2073843513 @default.
- W127962669 cites W2075258208 @default.
- W127962669 cites W2078049915 @default.
- W127962669 cites W2081030735 @default.
- W127962669 cites W2085025732 @default.
- W127962669 cites W2085286895 @default.
- W127962669 cites W2086483797 @default.
- W127962669 cites W2101668707 @default.
- W127962669 cites W2106949912 @default.
- W127962669 cites W2109844644 @default.
- W127962669 cites W2109946592 @default.
- W127962669 cites W2113753666 @default.
- W127962669 cites W2114647329 @default.
- W127962669 cites W2115940435 @default.
- W127962669 cites W2117924742 @default.
- W127962669 cites W2118010755 @default.
- W127962669 cites W2131110491 @default.
- W127962669 cites W2134465683 @default.
- W127962669 cites W2144886557 @default.
- W127962669 cites W2156023245 @default.
- W127962669 cites W2161574105 @default.
- W127962669 cites W2165746089 @default.
- W127962669 cites W4250364564 @default.
- W127962669 doi "https://doi.org/10.1007/978-1-4419-7002-2_16" @default.
- W127962669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20886767" @default.
- W127962669 hasPublicationYear "2010" @default.
- W127962669 type Work @default.
- W127962669 sameAs 127962669 @default.
- W127962669 citedByCount "6" @default.
- W127962669 countsByYear W1279626692012 @default.
- W127962669 countsByYear W1279626692013 @default.
- W127962669 countsByYear W1279626692014 @default.
- W127962669 countsByYear W1279626692015 @default.
- W127962669 countsByYear W1279626692021 @default.
- W127962669 crossrefType "book-chapter" @default.
- W127962669 hasAuthorship W127962669A5002597093 @default.
- W127962669 hasAuthorship W127962669A5006943587 @default.
- W127962669 hasConcept C104317684 @default.
- W127962669 hasConcept C127716648 @default.
- W127962669 hasConcept C1491633281 @default.
- W127962669 hasConcept C152662350 @default.
- W127962669 hasConcept C2779523775 @default.
- W127962669 hasConcept C2991704936 @default.
- W127962669 hasConcept C2994212657 @default.
- W127962669 hasConcept C522857546 @default.
- W127962669 hasConcept C54355233 @default.
- W127962669 hasConcept C55493867 @default.
- W127962669 hasConcept C62231903 @default.
- W127962669 hasConcept C63645605 @default.
- W127962669 hasConcept C70721500 @default.