FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W128022079> ?p ?o ?g. }

• W128022079 endingPage "68" @default.
• W128022079 startingPage "51" @default.
• W128022079 abstract "Diabetes mellitus (DM) is a growing health problem in the USA, afflicting over 18.2 million Americans. Morbidity and mortality from DM most commonly result from the long-term complications of the disease. “Intensive therapy” reduces blood sugars to near normal and effective management of other associated risk factors such as lipid abnormalities and blood pressure (BP). New clinical trials are being carried out to determine whether goals for intensive therapy should be lower than current goals and to test various therapeutic strategies to determine the optimum methods to prevent diabetes complications. Cardiovascular disease (CVD) disproportionately affects people with diabetes and is a leading cause of death. So far, intensive glycemic control has not been conclusively shown to decrease cardiovascular events. The therapeutic agents used in treating glycemia have different effects on cardiovascular risks and therefore may have different effects on outcome. Metformin was the only oral anti-diabetic medication shown to decrease cardiovascular events independent of glycemic control. Thiazolidinediones improve insulin resistance and lower insulin concentrations, which may be beneficial because hyperinsulinemia is an independent predictor of CVD. In the recent PROACTIVE study, a pioglitazone treatment was associated with a significant reduction in myocardial infarction and cardiovascular mortality, although that was not the primary endpoint of the study. Insulin therapy acutely reduces mortality and morbidity in patients with hyperglycemia when critically ill, but the effect on cardiovascular events is unclear. In contrast, insulin secretagogues have very little effect on both cardiovascular risk factors and outcomes. Thus, the role of intensive glycemic control and the choice of therapeutic agents to reduce the macrovascular complications of diabetes are unclear." @default.
• W128022079 created "2016-06-24" @default.
• W128022079 creator A5034671525 @default.
• W128022079 creator A5083798337 @default.
• W128022079 date "2008-01-01" @default.
• W128022079 modified "2023-09-27" @default.
• W128022079 title "Intensive Treatment and Complications of Diabetes" @default.
• W128022079 cites W1502524639 @default.
• W128022079 cites W1604542334 @default.
• W128022079 cites W1667957779 @default.
• W128022079 cites W1840840071 @default.
• W128022079 cites W1965140020 @default.
• W128022079 cites W1977386411 @default.
• W128022079 cites W1977879939 @default.
• W128022079 cites W1978021168 @default.
• W128022079 cites W1980431254 @default.
• W128022079 cites W1981420315 @default.
• W128022079 cites W1987899716 @default.
• W128022079 cites W1999775886 @default.
• W128022079 cites W2007437966 @default.
• W128022079 cites W2008288517 @default.
• W128022079 cites W2011656517 @default.
• W128022079 cites W2013529909 @default.
• W128022079 cites W2020866326 @default.
• W128022079 cites W2020984463 @default.
• W128022079 cites W2026229570 @default.
• W128022079 cites W2029012066 @default.
• W128022079 cites W2036421978 @default.
• W128022079 cites W2041244642 @default.
• W128022079 cites W2044437167 @default.
• W128022079 cites W2054973752 @default.
• W128022079 cites W2063392732 @default.
• W128022079 cites W2078089300 @default.
• W128022079 cites W2078130913 @default.
• W128022079 cites W2082807624 @default.
• W128022079 cites W2085557075 @default.
• W128022079 cites W2092061751 @default.
• W128022079 cites W2107545755 @default.
• W128022079 cites W2115112300 @default.
• W128022079 cites W2117520303 @default.
• W128022079 cites W2118828771 @default.
• W128022079 cites W2121065969 @default.
• W128022079 cites W2121776978 @default.
• W128022079 cites W2123946565 @default.
• W128022079 cites W2124977574 @default.
• W128022079 cites W2126781806 @default.
• W128022079 cites W2129186954 @default.
• W128022079 cites W2133891706 @default.
• W128022079 cites W2139634859 @default.
• W128022079 cites W2143112632 @default.
• W128022079 cites W2146975696 @default.
• W128022079 cites W2147792699 @default.
• W128022079 cites W2151169124 @default.
• W128022079 cites W2158822657 @default.
• W128022079 cites W2159969745 @default.
• W128022079 cites W2161310510 @default.
• W128022079 cites W2164367541 @default.
• W128022079 cites W2188846692 @default.
• W128022079 cites W2277297397 @default.
• W128022079 cites W2757208104 @default.
• W128022079 cites W2769264260 @default.
• W128022079 cites W4236581303 @default.
• W128022079 cites W4251505062 @default.
• W128022079 cites W4253337782 @default.
• W128022079 cites W4253435833 @default.
• W128022079 doi "https://doi.org/10.1007/978-1-59745-572-5_4" @default.
• W128022079 hasPublicationYear "2008" @default.
• W128022079 type Work @default.
• W128022079 sameAs 128022079 @default.
• W128022079 citedByCount "0" @default.
• W128022079 crossrefType "book-chapter" @default.
• W128022079 hasAuthorship W128022079A5034671525 @default.
• W128022079 hasAuthorship W128022079A5083798337 @default.
• W128022079 hasConcept C126322002 @default.
• W128022079 hasConcept C134018914 @default.
• W128022079 hasConcept C177713679 @default.
• W128022079 hasConcept C2777180221 @default.
• W128022079 hasConcept C2777391703 @default.
• W128022079 hasConcept C2777448766 @default.
• W128022079 hasConcept C2778384471 @default.
• W128022079 hasConcept C2779134260 @default.
• W128022079 hasConcept C2779306644 @default.
• W128022079 hasConcept C2780323712 @default.
• W128022079 hasConcept C2780473172 @default.
• W128022079 hasConcept C2780920962 @default.
• W128022079 hasConcept C2780988686 @default.
• W128022079 hasConcept C500558357 @default.
• W128022079 hasConcept C555293320 @default.
• W128022079 hasConcept C71924100 @default.
• W128022079 hasConceptScore W128022079C126322002 @default.
• W128022079 hasConceptScore W128022079C134018914 @default.
• W128022079 hasConceptScore W128022079C177713679 @default.
• W128022079 hasConceptScore W128022079C2777180221 @default.
• W128022079 hasConceptScore W128022079C2777391703 @default.
• W128022079 hasConceptScore W128022079C2777448766 @default.
• W128022079 hasConceptScore W128022079C2778384471 @default.
• W128022079 hasConceptScore W128022079C2779134260 @default.
• W128022079 hasConceptScore W128022079C2779306644 @default.

• next