Matches in SemOpenAlex for { <https://semopenalex.org/work/W128123082> ?p ?o ?g. }
- W128123082 abstract "Bladder cancer is a common malignancy and a frequent cause of cancer-related death worldwide. The benefit from current chemotherapy has reached a relative plateau, thus identification of molecular targets for better therapy is a high priority. Human epidermal receptors constitute a family of receptor tyrosine kinases, which appear to be implicated in cellular transformation and can be over-expressed in a variety of solid tumors. There is preclinical and clinical data suggesting the role of EGFR and HER2 in urothelial carcinoma, thus prompting clinical investigation of anti-HER targeted therapies attempting to inhibit HER-induced tumor-promoting signaling. There is significant and dynamic cross-talk between HER and other signaling pathways and the identification of the structure and function of such cellular networks in the setting of urothelial cancer is a complex and difficult task. The development of prognostic and predictive biomarkers is needed in order to improve the personalized management of patients with urothelial cancer." @default.
- W128123082 created "2016-06-24" @default.
- W128123082 creator A5023498238 @default.
- W128123082 creator A5026717218 @default.
- W128123082 creator A5041126882 @default.
- W128123082 date "2011-08-15" @default.
- W128123082 modified "2023-09-23" @default.
- W128123082 title "Urothelial carcinomas: a focus on human epidermal receptors signaling." @default.
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