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- W128349652 abstract "The solvent 2-nitropropane (2-NP) has been reported to produce liver necrosis and hepatocarcinoma in rats, males being much more sensitive than females (Griffin et al 1980). Since this may be caused by sex specific pharmacokinetics of 2-NP inhalation kinetics in male and in female Sprague-Dawley rats were investigated. Furthermore, as specific indicators of parenchymal hepatic injury the response of glutamic oxalacetic transaminase (GOT) and of glutamic pyruvic transaminase (GPT) was studied in serum after application of 2-NP to the animals." @default.
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- W128349652 date "1989-01-01" @default.
- W128349652 modified "2023-09-26" @default.
- W128349652 title "Pharmacokinetics and Hepatotoxicity of 2-Nitropropane in Rats" @default.
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- W128349652 doi "https://doi.org/10.1007/978-3-642-74117-3_63" @default.
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