Matches in SemOpenAlex for { <https://semopenalex.org/work/W128353583> ?p ?o ?g. }
- W128353583 endingPage "497" @default.
- W128353583 startingPage "471" @default.
- W128353583 abstract "The endogenous opioid systems constitute three distinct neuronal systems that are widely distributed throughout the central nervous system (CNS). The three opioid precursors found in these neurons, proopiomelanocortin (POMC), proenkephalin (PENK), and prodynorphin (PDYN), each contain numerous biologically active products that are released at the synaptic terminals of opioidergic neurons. These peptides exert their physiological actions by interacting with various classes of opioid receptor types (μ, δ, к) present on both pre- and postsynaptic membranes of opioid and opioid- target neurons. Opioid neurotransmission appears to influence many CNS functions, including nociception, cardiovascular regulation, respiration, neuroendocrine and neuroimmune activity, thermoregulation, and consummatory, sexual, aggressive, locomotor, and hedonic behavior, as well as learning and memory (Adler et al. 1988; Herz and Millan 1988; Khachaturian et al. 1988; Martinez et al. 1988; Pasternak 1988; Stefano 1989). Opioid peptides have also been implicated either directly or indirectly in the pathophysiology of several neurological, addictive, or psychiatric disorders, including Alzheimer’s, Parkinson’s, Huntington’s disease, stroke, epilepsy, brain and spinal cord injury, drug and alcohol addiction, eating disorders, manic-depressive illness, anxiety disorders, and schizophrenia (Nemeroff and Bissette 1986; Watson et al. 1986; Topel 1988; Kaye et al. 1989; Gulya 1990)." @default.
- W128353583 created "2016-06-24" @default.
- W128353583 creator A5023875259 @default.
- W128353583 creator A5036063369 @default.
- W128353583 creator A5057050856 @default.
- W128353583 date "1993-01-01" @default.
- W128353583 modified "2023-10-14" @default.
- W128353583 title "Anatomy and Function of the Endogenous Opioid Systems" @default.
- W128353583 cites W102608180 @default.
- W128353583 cites W129577910 @default.
- W128353583 cites W130172257 @default.
- W128353583 cites W1482335491 @default.
- W128353583 cites W1501139717 @default.
- W128353583 cites W1521269575 @default.
- W128353583 cites W1539006225 @default.
- W128353583 cites W1543598925 @default.
- W128353583 cites W1571366225 @default.
- W128353583 cites W1605641317 @default.
- W128353583 cites W1607238413 @default.
- W128353583 cites W1608277376 @default.
- W128353583 cites W1709659980 @default.
- W128353583 cites W1857277871 @default.
- W128353583 cites W1965860693 @default.
- W128353583 cites W1966958074 @default.
- W128353583 cites W1967384371 @default.
- W128353583 cites W1968989693 @default.
- W128353583 cites W1970024715 @default.
- W128353583 cites W1970251455 @default.
- W128353583 cites W1972249550 @default.
- W128353583 cites W1972836704 @default.
- W128353583 cites W1973178078 @default.
- W128353583 cites W1973670469 @default.
- W128353583 cites W1974670594 @default.
- W128353583 cites W1974828706 @default.
- W128353583 cites W1975814998 @default.
- W128353583 cites W1976649676 @default.
- W128353583 cites W1977565016 @default.
- W128353583 cites W1980604875 @default.
- W128353583 cites W1981547673 @default.
- W128353583 cites W1985726561 @default.
- W128353583 cites W1986075380 @default.
- W128353583 cites W1987458904 @default.
- W128353583 cites W1988125198 @default.
- W128353583 cites W1988806074 @default.
- W128353583 cites W1990731928 @default.
- W128353583 cites W1990746404 @default.
- W128353583 cites W1991206010 @default.
- W128353583 cites W1991603311 @default.
- W128353583 cites W1993665570 @default.
- W128353583 cites W1994133253 @default.
- W128353583 cites W1995587559 @default.
- W128353583 cites W1997302126 @default.
- W128353583 cites W1997963232 @default.
- W128353583 cites W1998785835 @default.
- W128353583 cites W1998927349 @default.
- W128353583 cites W2002105918 @default.
- W128353583 cites W2003172853 @default.
- W128353583 cites W2006679763 @default.
- W128353583 cites W2007227757 @default.
- W128353583 cites W2007470655 @default.
- W128353583 cites W2010051841 @default.
- W128353583 cites W2010531200 @default.
- W128353583 cites W2010579678 @default.
- W128353583 cites W2011376467 @default.
- W128353583 cites W2011645297 @default.
- W128353583 cites W2012072643 @default.
- W128353583 cites W2012392333 @default.
- W128353583 cites W2012463256 @default.
- W128353583 cites W2013143373 @default.
- W128353583 cites W2015063879 @default.
- W128353583 cites W2015205250 @default.
- W128353583 cites W2017097116 @default.
- W128353583 cites W2018126125 @default.
- W128353583 cites W2019730410 @default.
- W128353583 cites W2023439603 @default.
- W128353583 cites W2025314368 @default.
- W128353583 cites W2026926631 @default.
- W128353583 cites W2027184960 @default.
- W128353583 cites W2027694520 @default.
- W128353583 cites W2027745203 @default.
- W128353583 cites W2028158224 @default.
- W128353583 cites W2028230381 @default.
- W128353583 cites W2029466905 @default.
- W128353583 cites W2029996397 @default.
- W128353583 cites W2030007365 @default.
- W128353583 cites W2030255194 @default.
- W128353583 cites W2030266257 @default.
- W128353583 cites W2031766979 @default.
- W128353583 cites W2033018177 @default.
- W128353583 cites W2033091261 @default.
- W128353583 cites W2033455286 @default.
- W128353583 cites W2033470468 @default.
- W128353583 cites W2033680879 @default.
- W128353583 cites W2034150611 @default.
- W128353583 cites W2035162334 @default.
- W128353583 cites W2035303307 @default.
- W128353583 cites W2036455062 @default.
- W128353583 cites W2037247893 @default.