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- W128729440 abstract "The role of derivatization in improving chromatographic analysis is emphasized in this chapter, with special focus on procedures for performing derivatization. Chemical modifications of the analyte are discussed in relation to several roles played in gas chromatographic (GC) and high-performance liquid chromatographic analyses, such as (1) for making polar and/or nonvolatile compounds amenable for GC, (2) for the improvement of chromatographic separation, (3) for the enhancement of the detector sensitivity, (4) for the improvement of quantitation accuracy, (5) for the improvement of stability of the analyte, and (6) for improving chiral separations. Some special derivatization methods for improving compound identification are also discussed. Examples of analytes, derivatization reagents, and their accordance with the chromatographic process are systematically discussed." @default.
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- W128729440 date "2015-01-01" @default.
- W128729440 modified "2023-09-26" @default.
- W128729440 title "The Role of Derivatization in Chromatography" @default.
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- W128729440 doi "https://doi.org/10.1016/b978-0-444-54319-6.00009-8" @default.
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