Matches in SemOpenAlex for { <https://semopenalex.org/work/W128812423> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W128812423 endingPage "70" @default.
- W128812423 startingPage "S165" @default.
- W128812423 abstract "Patients with idiopathic autoimmune hemolytic anemia (AIHA) of warm antibody type usually respond to corticosteroid therapy. However a proportion of patients will have disease relapse after steroid-induced remission.To assess the incidence and the possible risk factors of the relapse in a cohort of patients with idiopathic AIHA.We conducted a retrospective and prospective study of 34 idiopathic AIHA patients regularly followed at the Division of Hematology during January 1973 to December 2006. The medical records were reviewed for active hemolytic events and relapses, episodes of infections, pattern of corticosteroids administration and tapering. Types and subtypes of autoantibodies were studied by column agglutination test (the gel test).One patient with cold agglutinin disease was excluded, leaving a total of 33 patients (24 with warm type, 9 with mixed warm and cold type AIHA) in the study. The incidence of relapse was 1.157 episodes/person/year. The mean duration of relapse after remission was 23 months. Episodes of recurrent hemolysis were more frequent when corticosteroid administration was tapered from high to low dose (10 mg/day of prednisolone) within two months compared with a longer than two-month tapering (38 vs. 11 episodes; p < 0.01). In addition patients receiving continuing low dose of corticosteroids (< or = 10 mg/day of prednisolone) for > 6 months had lower incidence of relapse and longer duration of remission than those with discontinuing the medication within 6 months (0.443 vs. 1.911 episodes/person/year, p < 0.01; 37.4 vs. 10.6 months, p < 0.01). Episodes of recurrent hemolysis were more frequently observed in patients with events of infection than those without infections (mean 7.69 vs. 2.81, p = 0.032). Types and subtypes of autoantibodies did not seem to influence relapse in AIHA.Short duration of maintenance and rapid tapering of corticosteroids and infections are possible risk factors of relapses/recurrent hemolysis in idiopathic AIHA." @default.
- W128812423 created "2016-06-24" @default.
- W128812423 creator A5004660960 @default.
- W128812423 creator A5034914721 @default.
- W128812423 creator A5037026101 @default.
- W128812423 creator A5066909674 @default.
- W128812423 date "2010-01-01" @default.
- W128812423 modified "2023-09-27" @default.
- W128812423 title "Incidence and risk factors of relapses in idiopathic autoimmune hemolytic anemia." @default.
- W128812423 cites W1560045389 @default.
- W128812423 cites W1964450510 @default.
- W128812423 cites W2065313719 @default.
- W128812423 cites W2362969807 @default.
- W128812423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20364571" @default.
- W128812423 hasPublicationYear "2010" @default.
- W128812423 type Work @default.
- W128812423 sameAs 128812423 @default.
- W128812423 citedByCount "9" @default.
- W128812423 countsByYear W1288124232014 @default.
- W128812423 countsByYear W1288124232016 @default.
- W128812423 countsByYear W1288124232017 @default.
- W128812423 countsByYear W1288124232018 @default.
- W128812423 countsByYear W1288124232019 @default.
- W128812423 countsByYear W1288124232022 @default.
- W128812423 countsByYear W1288124232023 @default.
- W128812423 crossrefType "journal-article" @default.
- W128812423 hasAuthorship W128812423A5004660960 @default.
- W128812423 hasAuthorship W128812423A5034914721 @default.
- W128812423 hasAuthorship W128812423A5037026101 @default.
- W128812423 hasAuthorship W128812423A5066909674 @default.
- W128812423 hasConcept C120665830 @default.
- W128812423 hasConcept C121332964 @default.
- W128812423 hasConcept C126322002 @default.
- W128812423 hasConcept C141071460 @default.
- W128812423 hasConcept C187212893 @default.
- W128812423 hasConcept C2776715498 @default.
- W128812423 hasConcept C2776760755 @default.
- W128812423 hasConcept C2777385706 @default.
- W128812423 hasConcept C2777884830 @default.
- W128812423 hasConcept C2778248108 @default.
- W128812423 hasConcept C2779134260 @default.
- W128812423 hasConcept C61511704 @default.
- W128812423 hasConcept C71924100 @default.
- W128812423 hasConceptScore W128812423C120665830 @default.
- W128812423 hasConceptScore W128812423C121332964 @default.
- W128812423 hasConceptScore W128812423C126322002 @default.
- W128812423 hasConceptScore W128812423C141071460 @default.
- W128812423 hasConceptScore W128812423C187212893 @default.
- W128812423 hasConceptScore W128812423C2776715498 @default.
- W128812423 hasConceptScore W128812423C2776760755 @default.
- W128812423 hasConceptScore W128812423C2777385706 @default.
- W128812423 hasConceptScore W128812423C2777884830 @default.
- W128812423 hasConceptScore W128812423C2778248108 @default.
- W128812423 hasConceptScore W128812423C2779134260 @default.
- W128812423 hasConceptScore W128812423C61511704 @default.
- W128812423 hasConceptScore W128812423C71924100 @default.
- W128812423 hasLocation W1288124231 @default.
- W128812423 hasOpenAccess W128812423 @default.
- W128812423 hasPrimaryLocation W1288124231 @default.
- W128812423 hasRelatedWork W1652641203 @default.
- W128812423 hasRelatedWork W1880645240 @default.
- W128812423 hasRelatedWork W1963996170 @default.
- W128812423 hasRelatedWork W1965253112 @default.
- W128812423 hasRelatedWork W1966545021 @default.
- W128812423 hasRelatedWork W1969290462 @default.
- W128812423 hasRelatedWork W1975338840 @default.
- W128812423 hasRelatedWork W1981933562 @default.
- W128812423 hasRelatedWork W1984204316 @default.
- W128812423 hasRelatedWork W1996047660 @default.
- W128812423 hasRelatedWork W2005039480 @default.
- W128812423 hasRelatedWork W2013848199 @default.
- W128812423 hasRelatedWork W2080653919 @default.
- W128812423 hasRelatedWork W2088163075 @default.
- W128812423 hasRelatedWork W2118404859 @default.
- W128812423 hasRelatedWork W2146614808 @default.
- W128812423 hasRelatedWork W2259054830 @default.
- W128812423 hasRelatedWork W3008143782 @default.
- W128812423 hasRelatedWork W3148495776 @default.
- W128812423 hasRelatedWork W5287291 @default.
- W128812423 hasVolume "93 Suppl 1" @default.
- W128812423 isParatext "false" @default.
- W128812423 isRetracted "false" @default.
- W128812423 magId "128812423" @default.
- W128812423 workType "article" @default.