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• W129062110 abstract "In this chapter, the use of multiwalled carbon nanotubes (MWCNTs) as sensors for healthy bone growth are discussed. MWCNTs are cytocompatible with osteoblasts (bone-forming cells) and enhance osteoblast calcium deposition, and thus, bone formation. Moreover, MWCNTs have been grown out of nanopores of anodized titanium (MWCNT-Ti), which has a surface layer of titanium oxide (a popular chemistry for orthopedic implants) to serve as a novel in situ orthopedic implant sensor. The electrochemical responses of MWCNT-Ti have been investigated in an attempt to ascertain if MWCNT-Ti can serve as novel in situ sensors for bone formation. MWCNT-Ti has been subjected to a ferri/ferrocyanide redox couple and its electrochemical behavior measured. Cyclic voltammograms (CVs) have demonstrated enhanced redox potentials of the MWCNT-Ti compared to Ti alone. These redox signals have been superior to that obtained from bare Ti, which does not sense either oxidation or reduction peaks in CV. Moreover, the redox reactions of MWCNT-Ti have been tested in a solution of extracellular bone components synthesized by osteoblasts in vitro . It has been found that MWCNT-Ti also exhibited well-defined and persistent CV, similar to the ferri/ferrocyanide redox reaction. The observed higher electrodic performance and electrocatalytic activity the MWCNT-Ti senses compared to bare Ti are likely because of the fact that MWCNTs enhance direct electron transfer and facilitate double-layer effects, leading to a strong redox signal. These collective results may encourage further study and modification of MWCNT-Ti to sense new bone growth in situ next to implants and perhaps to monitor other events (such as infection and/or scar tissue formation) to improve the current clinical diagnosis of orthopedic implant success or failure." @default.
• W129062110 created "2016-06-24" @default.
• W129062110 creator A5015651290 @default.
• W129062110 creator A5076201188 @default.
• W129062110 date "2017-01-01" @default.
• W129062110 modified "2023-10-17" @default.
• W129062110 title "3.32 Carbon Nanotubes: Applications for In Situ Implant Sensors" @default.
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• W129062110 doi "https://doi.org/10.1016/b978-0-08-100691-7.00156-7" @default.
• W129062110 hasPublicationYear "2017" @default.
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