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- W129941955 abstract "We present a review of studies examining the effect of homocysteine-lowering therapy in mildly hyper-homocysteinemic vascular patients. Pooled data showed that it is possible to decrease elevated fasting plasma homocysteine levels as much as a mean of 40% by the use of a low dose of 0.65 mg folic acid daily. A higher dose, i.e., 5 mg daily, resulted in a slightly larger reduction of about 50%; 10 mg folic acid daily had no extra effect. It is advisable to add vitamin B12 in a low oral dose of 0.400 mg daily both because of its modest homocysteine-lowering effect, but more to avoid folic acid—refractoriness in cases of vitamin B12 deficiency and to prohibit the development of neuropathy due to unrecognized perniciosa. Vitamin B6 does not affect fasting hyperhomocysteinemia." @default.
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- W129941955 date "1997-01-01" @default.
- W129941955 modified "2023-09-27" @default.
- W129941955 title "Treatment of Mild Hyperhomocysteinemia" @default.
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- W129941955 doi "https://doi.org/10.1007/978-1-4615-5771-5_15" @default.
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