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- W130313601 abstract "Ca2+ binding to troponin-C, a regulatory protein of muscle contraction, is an important step for the initiation of cardiac muscle contraction [1]. Therefore, the change in the intracellular Ca2+ concentration ([Ca2+]i) and the affinity of troponin-C for Ca2+ are intimately related to cardiac muscle contraction. In mammalian cardiac muscles, intracellular Ca2+, which initiates contraction, is mainly delivered by the sarcoplasmic reticulum (SR) [2]. Therefore, the factors that influence Ca2+ release from SR are considered to cause the alteration in contraction. In addition, the factors that alter Ca2+ uptake by SR also influence the magnitude and the time course of intracellular Ca2+ transients." @default.
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- W130313601 date "1996-01-01" @default.
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- W130313601 title "Intracellular Ca2+ Transients in Response to Step Length Changes in Aequorin-Injected Ferret Papillary Muscles" @default.
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