Matches in SemOpenAlex for { <https://semopenalex.org/work/W131092126> ?p ?o ?g. }
- W131092126 endingPage "20" @default.
- W131092126 startingPage "12" @default.
- W131092126 abstract "This study investigated the role of uncovered stent struts on late stent thrombosis (LST) after drug-eluting stent (DES) implantation with optical coherence tomography (OCT). Autopsy studies have identified delayed healing and lack of endothelialization of DES struts as the hallmarks of LST. DES strut coverage has not previously been examined in vivo in patients with LST. We studied 54 patients, including 18 with DES LST (median 615 days after implant) undergoing emergent percutaneous coronary interventions and 36 matched DES control subjects undergoing routine repeat OCT and intravascular ultrasound (IVUS) who did not experience LST for ≥3 years. Thrombus aspiration was performed during emergent percutaneous coronary intervention before OCT and IVUS assessment. By OCT, patients with LST—compared with control subjects—had a higher percentage of uncovered (median [interquartile range]) (12.27 [5.50 to 23.33] vs. 4.14 [3.00 to 6.22], p < 0.001) and malapposed (4.60 [1.85 to 7.19] vs. 1.81 [0.00 to 2.99], p < 0.001) struts. The mean neointimal thickness was similar in the 2 groups (0.23 ± 0.17 mm vs. 0.17 ± 0.09 mm, p = 0.28). By IVUS, stent expansion was comparable in the 2 groups, although positive remodeling was increased in patients with LST (mean vessel cross-section area 19.4 ± 5.8 mm2 vs. 15.1 ± 4.6 mm2, p = 0.003). Thrombus aspiration demonstrated neutrophils and eosinophils in most cases. By multivariable analysis, the length of segment with uncovered stent struts by OCT and the remodeling index by IVUS were independent predictors of LST. In this in vivo case-controlled study, the presence of uncovered stent struts as assessed by OCT and positive vessel remodeling as imaged by IVUS were associated with LST after DES." @default.
- W131092126 created "2016-06-24" @default.
- W131092126 creator A5019847145 @default.
- W131092126 creator A5025740013 @default.
- W131092126 creator A5037374990 @default.
- W131092126 creator A5039499666 @default.
- W131092126 creator A5046629853 @default.
- W131092126 creator A5057098758 @default.
- W131092126 creator A5059983020 @default.
- W131092126 creator A5070231050 @default.
- W131092126 creator A5071287538 @default.
- W131092126 creator A5073353856 @default.
- W131092126 creator A5085522985 @default.
- W131092126 creator A5088861691 @default.
- W131092126 date "2012-01-01" @default.
- W131092126 modified "2023-09-29" @default.
- W131092126 title "Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis" @default.
- W131092126 cites W114687431 @default.
- W131092126 cites W146325010 @default.
- W131092126 cites W1966093874 @default.
- W131092126 cites W1968528328 @default.
- W131092126 cites W1973793184 @default.
- W131092126 cites W1988806137 @default.
- W131092126 cites W1989556574 @default.
- W131092126 cites W1993222177 @default.
- W131092126 cites W2004202587 @default.
- W131092126 cites W2011659568 @default.
- W131092126 cites W2020697752 @default.
- W131092126 cites W2030380355 @default.
- W131092126 cites W2035107629 @default.
- W131092126 cites W2051879007 @default.
- W131092126 cites W2061741372 @default.
- W131092126 cites W2078044868 @default.
- W131092126 cites W2083630382 @default.
- W131092126 cites W2087150869 @default.
- W131092126 cites W2103766009 @default.
- W131092126 cites W2105332661 @default.
- W131092126 cites W2119470649 @default.
- W131092126 cites W2129811129 @default.
- W131092126 cites W2146743728 @default.
- W131092126 cites W2157080081 @default.
- W131092126 cites W2206396373 @default.
- W131092126 cites W2412291070 @default.
- W131092126 cites W2945399066 @default.
- W131092126 cites W4253237537 @default.
- W131092126 cites W70265140 @default.
- W131092126 doi "https://doi.org/10.1016/j.jcin.2011.09.018" @default.
- W131092126 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22230145" @default.
- W131092126 hasPublicationYear "2012" @default.
- W131092126 type Work @default.
- W131092126 sameAs 131092126 @default.
- W131092126 citedByCount "306" @default.
- W131092126 countsByYear W1310921262012 @default.
- W131092126 countsByYear W1310921262013 @default.
- W131092126 countsByYear W1310921262014 @default.
- W131092126 countsByYear W1310921262015 @default.
- W131092126 countsByYear W1310921262016 @default.
- W131092126 countsByYear W1310921262017 @default.
- W131092126 countsByYear W1310921262018 @default.
- W131092126 countsByYear W1310921262019 @default.
- W131092126 countsByYear W1310921262020 @default.
- W131092126 countsByYear W1310921262021 @default.
- W131092126 countsByYear W1310921262022 @default.
- W131092126 countsByYear W1310921262023 @default.
- W131092126 crossrefType "journal-article" @default.
- W131092126 hasAuthorship W131092126A5019847145 @default.
- W131092126 hasAuthorship W131092126A5025740013 @default.
- W131092126 hasAuthorship W131092126A5037374990 @default.
- W131092126 hasAuthorship W131092126A5039499666 @default.
- W131092126 hasAuthorship W131092126A5046629853 @default.
- W131092126 hasAuthorship W131092126A5057098758 @default.
- W131092126 hasAuthorship W131092126A5059983020 @default.
- W131092126 hasAuthorship W131092126A5070231050 @default.
- W131092126 hasAuthorship W131092126A5071287538 @default.
- W131092126 hasAuthorship W131092126A5073353856 @default.
- W131092126 hasAuthorship W131092126A5085522985 @default.
- W131092126 hasAuthorship W131092126A5088861691 @default.
- W131092126 hasBestOaLocation W1310921261 @default.
- W131092126 hasConcept C119060515 @default.
- W131092126 hasConcept C126322002 @default.
- W131092126 hasConcept C126838900 @default.
- W131092126 hasConcept C164705383 @default.
- W131092126 hasConcept C2776931568 @default.
- W131092126 hasConcept C2777546689 @default.
- W131092126 hasConcept C2778283817 @default.
- W131092126 hasConcept C2778583881 @default.
- W131092126 hasConcept C2778818243 @default.
- W131092126 hasConcept C2780400711 @default.
- W131092126 hasConcept C2780868729 @default.
- W131092126 hasConcept C2781362458 @default.
- W131092126 hasConcept C500558357 @default.
- W131092126 hasConcept C71924100 @default.
- W131092126 hasConceptScore W131092126C119060515 @default.
- W131092126 hasConceptScore W131092126C126322002 @default.
- W131092126 hasConceptScore W131092126C126838900 @default.
- W131092126 hasConceptScore W131092126C164705383 @default.
- W131092126 hasConceptScore W131092126C2776931568 @default.
- W131092126 hasConceptScore W131092126C2777546689 @default.